Hepcinat-LP - instructions for use. Treatment regimen with Hepcinat LP
Hepcinat-LP with Sofosbuvir and Ledipasvir is a combination drug against the hepatitis virus. Next, we will tell you where you can buy the drug, at what price and how to use the company’s official website for this. We will also present the instructions in Russian and introduce you to the reviews left by satisfied and healthy customers.
Hepcinat-LP is a medicine that shows its activity in the fight against chronic liver disease, accompanied by genotype 1 with or without cirrhosis of the liver. Sofosbuvir and Ledipasvir, which are part of the drug Hepcinat-LP, serve to suppress a pair of proteins that provoke the multiplication of the virus.
Hepsinate LP is an officially confirmed generic version of the very expensive drug Harvoni. Despite the lack of patent protection, treatment with this drug has equivalent effectiveness and safety to the original, as it is manufactured in strict accordance with quality standards.
Price and where to buy Hepcinat-LP
The bureaucratic cycle prevents the release of such effective means, like Hepcinat-LP, therefore, even in pharmacies in large cities (Moscow, etc.) they can offer to buy only branded medicines at high prices.
Due to the popularity of the medicine and its effect, there is a risk of becoming a victim of scammers who are ready to offer more low price. Structure original drug consists of two active substances that, when combined, have a powerful effect: Sofosbuvir and Ledipasvir.
The official website works directly with manufacturers from India, so to order generic Hepcinat-LP, you need to provide feedback and then follow the instructions of the online pharmacy manager. This form of cooperation allows us to maintain optimal costs, as well as comply with all requirements for the quality of medicines.
All Heptsinat LP products are certified. Only original product purchased from official representative, can rid the body of hepatitis.
How much does Hepcinat-LP cost:
- Moscow - 19,500 rub.
- St. Petersburg - 19,500 rub.
- Khabarovsk - 19,500 rub.
- Ekaterinburg - 19,500 rubles.
- Ukraine, Kyiv - 9350 UAH.
- Dnepropetrovsk - 9350 UAH.
- Minsk - 570 bel. rubles
- Almaty - 109,000 tenge.
Reviews from doctors about Hepcinat-LP
Most of the doctors' reviews about Hepcinat-LP have positive character. This is due to the fact that many patients were able to achieve a positive effect from the treatment of hepatitis C. Doctors from Russian clinics share their experience with this drug.
My patient was infected with hepatitis C during surgery abroad. She came to my appointment in tears and panic. Not everyone can afford to buy this expensive medicine like Harvoni. However, for the general population there are available funds, called generics, are a worthy replacement for well-promoted brands.
I decided to advise her on Hepcinat LP, since I already had successful experience in using it against hepatitis C, so I had no fears and was confident in positive effect Moreover, the country of origin of this product is India, which has proven itself in this field. And in once again I turned out to be right: after a month, the tests improved, and after completing the entire course of treatment, the virus was not detected.
Alexey Petrovich P., hepatologist (therapist)
For the first time I came across the Indian drug Heptsinate LP this spring. I already had quite a lot of experience in treating viral hepatitis C, but never once did I dare to use this remedy. A patient came to me who himself suggested and even slightly insisted on treatment with Heptsinate. We ordered it on the official website. I agreed because I knew that Sofosbuvir and Ledipasvir in combination have a strong effect on the disease and I had read the reviews myself more than once. The drug worked, the powerful antiviral effect relieved the disease. I would like to emphasize that treatment with such a medicine should only occur under the supervision of specialists.
Elena Viktorovna D., specialist in viral diseases
Patient reviews of Hepcinat-LP
On at the moment Hepcinat-LP has already gained great popularity, so you can find numerous patient reviews on the Internet. Most of them are inclined to believe that the drug is strong remedy and is able to overcome the disease.
After I discovered this illness, I immediately began looking for the most effective remedy, because it became very scary. After reading numerous reviews on the forum about the drug, I decided to buy it on the official website, which was recommended by the doctor, and I was not mistaken.
After the first month, the generic showed the first positive result, my happiness knew no bounds! I took the course to the end and got rid of the virus completely, I recommend it to everyone!
Maria, 33 years old, Rostov-on-Don
Before buying Hepsinat LP, I decided to familiarize myself with the components and active substances, since I sometimes experience allergic reactions. But Ledipasvir, Sofosbuvir and other components turned out to be safe for me.
I guess I was a little hasty when, after the first two weeks of treatment, I wanted to see an improved situation, but this did not happen, and the doctor advised me to wait a little and come back in at least a month and a half. I did just that. When I saw the results, I couldn’t believe my eyes: the virus had disappeared! I really hope he doesn't come back again.
Alexander, 41 years old, Moscow
Instructions for use Hepcinat-LP
The instructions for use in Russian indicate what to do and how to use Hepcinat-LP Natco correctly. The basic rules for taking the drug, composition and contraindications for use will be presented below.
Hepcinate LP should be taken one tablet once a day with meals, at the same time.
Food can be high-calorie (1000 kcal) or less - 600 kcal, and be 50% or 25% fat, respectively. The instructions also indicate that taking the drug on an empty stomach will not reduce the antiviral effect.
Important! Tablets must not be divided into parts, diluted with water or crushed to a powder state. They are taken in full, at the same time every day. This is one of the conditions for complete recovery.
If for some reason the patient misses a dose during treatment, this does not mean that the next time you need to take two tablets. Because if you take more, side effects may occur from an excess of Ledipasvir and Sofosbuvir in the body, and you may experience anaphylactic shock.
The medicine is intended for patients with genotype 1 hepatitis.
There are certain risks of relapse, which depend on the following factors:
- The presence or absence of liver cirrhosis.
- The severity of the disease.
- Presence of HIV infection.
- Associated viruses.
Contraindications
Were held laboratory tests contraindications to taking the drug Hepcinat-LP. The instructions indicate that you should not take the product in the following cases:
- if the patient is under 18 years of age;
- during pregnancy and during breastfeeding;
- since the drug contains Sofosbuvir, overdose should be avoided;
- It is not advisable to take simultaneously with alcohol;
- prohibited for patients with severe liver cirrhosis;
- allergic reaction.
Treatment with medication should only be carried out under the strict supervision of the attending physician!
There is also a list of products with which Hepcinat-LP is not compatible. In order not to cause side effects, and the treatment of hepatitis has proven to be effective, taking the medicine should not be accompanied by simultaneous administration such means as:
- rifampin;
- elvitegravir;
- carbamazepine;
- tipranavir;
- St. John's wort;
- phenytoin;
- rosuvastatin;
- tenofovir
- emtricitabine.
How to remove Hepsinate LP from the body?
Doctors say that it will not be possible to remove excess Hepsinate LP from the body. Since even through hemodialysis, Ledipasvir is very difficult to remove due to its tight adhesion to plasma proteins.
How to distinguish a fake Hepcinat-LP?
Since the medicine cannot be classified as a cheap drug, it is very important not to stumble upon a counterfeit and to know what the tablets look like, because we're talking about about human health.
Original tablets Hepcinat-LP have an oval shape of a greenish color with a special glaze coating. On one side of the tablet there is the inscription SL.
Each of the branded shells will contain 28 tablets and a special silicate gel is placed inside to absorb moisture. To once again check the authenticity of the product, you can make sure that there is a seal made of polyester.
Indications for use of Hepcinat-LP
Hepcinat-LP, which contains two active components Sofosbuvir and Ledipasvir, intended for the treatment chronic virus hepatitis C genotype 1, only in adults. A safe intake for the body involves a daily dose of Hepcinate LP, which should not exceed one tablet with meals or on an empty stomach. It is advisable that the drug be taken at the same time every day.
Clinical studies have proven that regular use of the Indian drug allows, first of all, to stop the process of viral cell division, which significantly reduces the risk of developing inflammation and fibrosis even in the most running forms diseases.
What does Heptsinate LP contain?
The drug Hepcinat-LP, in addition to two main components, namely Sofosbuvir (400 mg) and Ledipasvir (90 mg), includes several inactive substances, including:
- Silicon dioxide (colloidal).
- Magnesium stearate.
- Cellulose grains.
- Copovidon.
- Croscamelose sodium.
Almost the same excipients are included in the medicine for the treatment of Harvoni hepatitis, the new generic of which is Heptsinate LP.
From the same manufacturer Nacto Pharma. The drug is active in the fight against hepatitis C genotypes 1, 2, 3, 4. Its active substances are Daclatasvir and Sofosbuvir, which allows the drug to effectively fight liver diseases.
Video: Treatment of hepatitis C Hepcinat-LP with Sofosbuvir and Ledipasvir
| RATING | |
| Efficiency | |
| Safety | |
| Availability | |
| RESULT Based on reviews from doctors and patients who have completed a full course of treatment with Heptsinate LP, we can conclude that the medicine can really help, saving the patient from a serious illness. Do not despair if the drug does not help after the first course of treatment. A repeated course increases the chances of full recovery, since the effect of the means and treatment regimens is improved, thereby increasing the effectiveness. | FINAL RESULT |
Hepcinat LP (active ingredients ledipasvir / 90 mg and sofosbuvir / 400 mg) is used in the treatment of hepatitis C virus (HCV) in chronic form. Hepatitis C refers to viral infections, causing inflammatory processes in the liver.
The active ingredients of the drug prevent the virus from multiplying in the body, while simultaneously blocking its entry into healthy cells.
This drug has international trade name– Harvoni is its generic (analogue). Generics of Harvoni appeared in India immediately after Gilead Sciences, USA, issued licenses for the production of a new effective means fight against hepatitis C.
Indian generics appeared on the pharmaceutical market after the signing of an agreement to implement an international program to combat HCV. And initially they were intended primarily for the population of low-income countries, in which, due to low level In the development of medicine, there is no possibility of controlling the epidemiological situation and maintaining its required level.
As a result, the drug Heptsinate LP became pharmacokinetically bioequivalent to the original Harvoni. And its effect on the body allows us to provide effective therapy HCV genotypes 1 and 4. Moreover, the probability of cure for genotype 1 reaches 94% - 99%.
Hepcinat LP helps prevent HCV from progressing in the body by gradually weakening the virus and actively preventing it from spreading further by blocking the ability to replicate.
At the same time, a licensed medicine costs significantly (several tens of times) cheaper than its original, manufactured in the USA, which makes it possible to purchase Indian generics significantly more patients.
Active ingredient: sofosbuvir / ledipasvir Dosage: 400 mg / 90 mg Name: Hepcinat LP - generic Harvoni (Harvoni) Manufacturing company: Natco Pharma Ltd., India Indications: intended for the treatment of HCV genotypes 1 and 4 in patients with or without liver cirrhosis. Effective for primary patients who have not previously undergone treatment, as well as for those who have unsuccessful experience of HCV therapy using interferons and ribavirin, as well as for those who have been identified as individual intolerant to the above drugs.
How it works
As an antiviral drug, sofosbuvir is a nucleotide polymerase inhibitor. The substance blocks the enzyme RNA polymerase, which is necessary for the reproduction of viruses. This reduces the amount of HCV in the blood.
Reducing viral replication leads to a decrease in the amount of hepatitis C virus in the body. Thus, a reduction in liver damage and an improvement in its functionality is achieved.
The medicine is produced in the form of oval-shaped tablets enclosed in special shell, easily dissolving in the stomach. Each tablet contains ledipasvir 90mg / sofosbuvir 400 mg. A plastic bottle with 28 tablets is housed in a cardboard package.
For a course of treatment containing 28 such tablets, and for therapy lasting 12 weeks, three such packages are required.
Benefits of Heptsinate LP
Compared to previously used treatment regimens using interferon and ribavirin, Hepcinat LP has many advantages:
- it is intended for monotherapy and therefore does not need to be combined with interferons and ribavirin;
- The previously used treatment regimen not only caused a lot of undesirable side effects, but was also ineffective. The probability of healing the sick did not exceed 40 - 50%;
- the use of Hepcinat LP for treatment caused almost no side effects, since the medicine itself is slightly toxic;
- significantly lower cost of therapy. A course of treatment using Harvoni will cost on average approximately $70 thousand, while a similar course with an Indian generic will not exceed $1.5 thousand;
- the drug is highly effective. With a course of treatment lasting 12 weeks, patients with HCV genotype 1 are completely cured with a probability of 96 - 99%. So high performance confirmed by studies in which 865 patients with hepatitis C genotype 1 took part;
- ease of administration by patients - two substances are contained in one tablet, which is undoubtedly much more convenient than taking two different ones medicines. If you want to be cured, you take one tablet a day for 12 weeks (for the first genotype, previously untreated).
Indications for use
Hepcinate LP is indicated for HCV treatment in adult patients with virus genotypes 1 and 4.
This drug is considered one of the most promising, created specifically for the treatment of HCV.
The effectiveness and safety of its use have been confirmed by six clinical trials, V
which involved approximately 2 thousand patients. Application in combination therapy sofosbuvir and ledipasvir instead of interferons, which have unpleasant side effects, significantly improves the comfort of therapy for patients with HCV.
Dosage and method of administration
Duration of therapy
The likelihood of a relapse is influenced by the initial circumstances associated with the virus itself and its host, as well as the duration of therapy.
The duration of treatment also depends on the initial circumstances. Recommended duration of therapy with Hepcinate LP:
- for primary patients with/without cirrhosis - 12 weeks;
- for previously treated patients without cirrhosis - 12 weeks;
- for previously treated patients with cirrhosis - 24 weeks.
In some cases, Hepcinat LP can be taken for 8 weeks. This is practiced in primary patients who do not have cirrhosis, whose viral load is less than 6 million units/ml.
There is no need for dosage adjustment in patients with mild or moderate renal impairment. Dosage recommendations for patients with severe violations kidney function or terminal stage renal failure, are not currently developed.
Like any medicine, Hepcinat LP has certain contraindications for treatment, if present, it is not recommended to take it:
- in case of identified allergy to one of the active ingredients and also if you are already taking another drug containing sofosbuvir (to avoid overdose);
- for kidney problems, cirrhosis or liver transplantation, HIV infection and others serious illnesses you should inform your doctor;
- It is prohibited for anyone under 18 years of age to take the medicine, as well as for women during pregnancy or breastfeeding;
- take the drug very carefully in case of renal and liver failure;
- the effectiveness of treatment is reduced if rifampin and tipranavir, St. John's wort and carbamazepine, as well as rosuvastatin are taken together with Hepcinat LP.
Side effects
Most patients tolerate the drug well, without observing a noticeable deterioration in their well-being. Side effects that are common with Hepcinat drugs include:
- increased fatigue;
- the occurrence of frequent headaches;
- the appearance of diarrhea and insomnia.
Patients should be most attentive in the very first days of taking the drug, carefully monitoring all possible changes in your own body.
In some cases, a slow rhythm of heart activity was noticed. If a patient is taking medications that stimulate cardiac activity, the attending physician should be notified.
If the patient is at risk, and immediately after taking Hepcinat LP he experiences shortness of breath, pain in the heart, or severe migraine, he should quickly seek medical help.
Dosage forms
Each tablet contains 90 mg of ledipasvir and 400 mg of sofosbuvir. Hepcinate LP should be taken once a day, regardless of food intake, after swallowing one tablet and washing it down with plain water. It is advisable to do this strictly at the same time, which allows you to maintain a constant concentration of active substances in the body, increasing the effectiveness of therapy.
The tablet is swallowed whole, without dividing into parts or chewing. If you miss one dose, you can next pill take at the same time. If little time has passed since the overdue dose (no more than 17 hours), then you can take the pill when you remember about it.
In no case should you take two tablets at once to make up for a missed dose, as this may cause an overdose. Neither bad nor wellness cannot become a reason to interrupt the medication.
During the course of therapy, you should carefully monitor your own feelings. If significant deviations from the norm are detected, you should immediately inform your doctor.
If during treatment the ineffectiveness of the drug is revealed, the doctor can change the treatment regimen, including prescribing other drugs to optimize therapy. The standard course of therapy for HCV genotype 1 lasts 12 weeks. For patients with a compensated stage of liver cirrhosis, the course duration is increased to 24 weeks.
The same applies to those patients who are undergoing treatment not for the first time. The duration of the course is determined by the doctor; only he has the right to change the dosage or duration of treatment.
Storage
It should be remembered that the drug Heptsinate LP is negatively related to high humidity and changes in temperature. For this reason, it should be stored in a dry place, out of the reach of sunlight and children.
The storage temperature should be in the range of +15 - +30ºС. When purchasing the drug, pay attention to the date of manufacture (indicated on the packaging) and remember that the shelf life of unopened packaging does not exceed two years. Taking expired medicine is strictly prohibited. You also need to know that after opening the package, the validity period decreases.
Since temperature regime storage is limited, transportation of Hepcinat LP is carried out in special thermal containers. When receiving the ordered drug, pay attention to how it is delivered to you and whether the transportation conditions comply with storage rules.
How to avoid counterfeiting
Surely many have noticed that in our world popular brands are often counterfeited. This applies to clothes, shoes, electronics. The tendency to counterfeit everything, including medicines, has not escaped.
Well-known Indian generics are counterfeited no less often than branded clothing or shoes.
True, with the difference that no one dies from counterfeit clothing, and if you come across a fake Hepcinat LP, then it is possible serious problems with health up to death.
Therefore, when choosing an online store to purchase Heptsinate LP, pay attention to several nuances:
- the period of his work in the pharmaceutical market. This will allow you to avoid shell companies created for one-time use. If a store has been around for a long time and has a strong reputation, no one will ruin their own business for the sake of short-term profit, and therefore encountering a counterfeit there is unlikely;
- availability of documents confirming the legality of the activity: sales licenses medicines, invoices and contracts for the supply of products. Do not ignore the conditions for transporting medicines; reputable companies organize transportation no less reputably;
- carrying out input control on incoming goods. This is done precisely in order to exclude the possibility of supplying low-quality drugs to customers;
- the price at which medicines are sold. It should not deviate significantly from the weighted average in the pharmaceutical market, either upward or downward. The offer of Hepcinat LP at a deliberately low price should immediately call into question the quality of such a drug. At all Indian enterprises producing generics, selling prices are fixed. Therefore, no one will trade at a loss for themselves.
In addition to checking documents, you should be careful when examining the packaging of the medicine you receive. It is necessary that:
- the packaging must not be opened;
- the serial numbers printed on the bottle and cardboard packaging must match;
- the bottle must have a special cap that turns when twisted and opens only after pressing;
- holographic foil fit tightly to the neck of each bottle;
- The package contained instructions for use written in English.
These simple tricks help you avoid purchasing a counterfeit.
Where to buy Heptsinat LP in Russia
It should be noted right away that the drug is not sold in Russian pharmacies. Gilead Sciences, issuing a production license, banned the export of cheap Indian generics to a number of countries, including all European countries and Russia, among others.
Therefore, you can buy it in online stores, from private individuals, or by going to India and purchasing it at a pharmacy there. If you can’t make a choice, don’t get lost, call our store or simply leave a request on the website.
We will help you resolve all your questions during free consultation experienced hepatologist. To receive the ordered medicine, no advance payments are required, all payments are made upon receipt of the goods. And delivery within the Russian Federation is generally free, so buying Hepcinat LP in Russia is no longer a problem.
If you need to cure hepatitis C, then order the medicine and start therapy, you only have one health and it should be protected by getting rid of the virus in a timely manner.
Indications and contraindications
Hepcinat-LP is an Indian generic of the original drug Havroni, produced by the American company Gilead Sciences. This newest drug, which helps to cope with hepatitis C in just one course of treatment, which ensures its popularity and positive reviews on the pharmaceutical market around the world. However, the high cost of the original drug makes it impossible for people with middle and low incomes to buy it. Thus, the generic Hepcinat-LP appeared - the Indian analogue of Khavroni, which retains its effectiveness, but at the same time has a much lower price.
The medicine is used for effective treatment hepatitis C of the first and fourth genotypes, and is also recommended for patients who have stopped standard therapy By various reasons. Hepcinate-LP is also effective for patients with cirrhosis or other liver disorders. Reviews of the treatment in Russian, as well as the results of studies and tests confirming the effectiveness of the generic, can be read on the manufacturer’s official website.
The course of treatment is calculated by the attending physician and depends on the genotype of the virus, organ damage and duration of the disease, as well as various individual characteristics the patient's body. It is prohibited to use the drug without prior consultation with a hepatologist - this can both reduce the effectiveness of the drug and lead to anaphylactic shock when calculating the wrong dosage.
According to official instructions Hepcinat-LP in Russian and numerous studies, the effect of the drug is to block the ability of the hepatitis C virus to multiply. Ledipasvir acts as an inhibitor of the main protein necessary for the replication of hepatitis C, and sofosbuvir, in turn, blocks liver enzymes that contribute to the replication of the virus. According to original instructions Hepcinat-LP Natco, this allows you to stop the migration of the virus throughout the body, and also prevents its spread and reproduction.
Instructions for use of Hepcinat-LP contain contraindications in which the course of treatment may be ineffective. The drug is prohibited from use:
- children and adolescents under 18 years of age, since the drug has not been tested on patients at this age;
- pregnant women and women during the feeding period. To prevent pregnancy, you must use any available contraceptives;
- together with other antiviral drugs.
Limitations in use
In the presence of renal or liver failure The patient can take the medicine only under the strict supervision of the attending physician. However, as a rule, in these cases, the dosage is not changed, and the course of treatment does not differ from the standard regimen.
Patients who have problems with the heart and are taking appropriate medications to stimulate its activity are at risk. In particular, the drug amiodarone, when interacting with the constituents of Hepcinat-LP, can cause cardiac arrest and also cause symptomatic bradycardia.
Two in one!
Grade: 5
Hepcinat LP combines Ledipasvir and Sofosubvir, which prevent the spread of the virus in hepatitis C. Together, these ingredients work much more effectively. The doctor prescribed it to me complex therapy. After the course of the drug, my blood tests showed significant reduction viral load and improvement general condition health.
I had no side effects, my body accepted the drug well. Manufacturer - India, this is a generic or a copy of the American drug Harvoni, but at a more affordable price. There were doubts about the effectiveness, but after the first results they disappeared.
Grade: 5
Hepcinat LP was recommended by doctor. To begin with, it took 3 months, and then - depending on the results of the treatment. Peculiarity this drug The fact is that 1 tablet contains 2 necessary components at once and their dosage is selected in such a way that they are well absorbed by the body. These tablets are packed in 28 pieces, you can take a jar with you if you are going on a business trip. The doctor strongly recommended taking the appointment at the same time.
I had to give up many pleasures in food. From time to time there was a feeling of heaviness in the stomach, but I did not associate it with taking pills, this had happened to me before. A month later, I saw a doctor and had some tests done. He, looking at the results, allowed further use of the drug. After 12 weeks of taking Hepcinat LP, she passed the full set of required tests. The results are encouraging. I would like to believe that I am completely cured.
Grade: 5
I'm suffering viral hepatitis This is not the first year. Because of this serious illness, I had to endure many problems and sorrows. I contacted a huge number of specialists and tried treatment by various means: from traditional methods before courses of ribavirin and interferon.
After the last unsuccessful course of ribavirin, my doctor recommended a drug called Hepcinat. This medicine belongs to the group of generics. Once in the body, it affects enzymes in such a way that the virus stops multiplying.
What captivated me was that the manufacturer gives a 95% chance of recovery. I purchased the drug officially through dealers. Despite the fairly substantial amount, I still completed the 12-week course. You need to take the tablets very carefully, no more than one at a time. This is important because there is a risk of anaphylactic shock.
During the course I had some problems side effects: nausea, diarrhea, and general fatigue. By the end of the course, all this had practically disappeared. After completing the course, my tests turned out to be clear, there was no more virus in my blood, which I am very happy about!
Grade: 5
I found out about the presence of hepatitis C when I was tested for planned surgery. The analysis turned out to be positive. I had to start treatment urgently.
According to the doctor, the sooner treatment is started, the more likely it is to achieve a quick recovery. There is no need to think that hepatitis C cannot be treated. Now you can completely destroy the virus in the body and continue to live a normal life.
Of course, high-quality treatment is expensive and time-consuming. You need to be prepared for this. For example, I lost a lot of weight during the treatment period, as my body did not tolerate the drug very well. I took Hepcinat LP.
In my case, there were side effects from taking the drug. This is fine. The main thing is that everything needs to be reported to the doctor so that he can control the situation and, if necessary, replace the drug in time.
Hepcinat LP combines sofosbuvir and ledipasvir. Its price is cheaper than the original drug, but the effectiveness is the same.
In total, I took the pills for about 7 months. Hope very much quick result not worth it. My doctor immediately told me that it would be very difficult to completely get rid of the virus, but I still succeeded.
Now I am completely healthy and hope that I will not have to undergo treatment anymore.
Grade: 5
At first I doubted this generic: it costs much less than the original from Europe, the drug is complex, and not like the others, where sofosbuvir and ledipasvir are separated, the origin is generally Indian. In addition, my hepatitis was aggravated by liver fibrosis, in addition, my lifestyle was not particularly healthy - smoking and alcohol.
Before this, I took a course of injections with Pegasys, was in the hospital - it did not help, ribavirin also had an ambiguous effect, the relief was temporary. But Hepcinat is working well so far, because it does not so much strengthen the immune system as previous drugs, but rather fights directly against the virus itself. In addition, the course of treatment is simpler, there is no need to combine several tablets, everything is in one tablet. And now I’m only being examined as an inpatient, the need to stay in the hospital has disappeared, and with relief I was able to return to full life. AST and ALT in the blood quickly returned to normal, and fibrosis also began to decrease. The course has not yet been completed, but I notice an improvement based on my own feelings, and not just based on test data. In principle, after almost two months of treatment it’s pretty good, there’s still another month ahead according to the instructions, the virus should be eliminated completely.
Grade: 5
When hepatitis C was diagnosed and the question of a treatment method arose, I immediately refused Russian medications. There was an example of a father with the same diagnosis, he suffered greatly from side effects. Therefore, I chose generics, and of them, Hepcinat LP, because it combines Ledipasvir and Sofosubvir. These drugs are always prescribed in pairs, but here 2 in 1, you can save money.
I decided to buy two cans to begin with and I was right, because in two months I managed to recover. I didn’t believe it, the doctor didn’t believe it either, he ordered a bunch of tests, but they all showed that there were only antibodies in the blood and no viruses. In two months. Our doctors are stubborn, they believe either in their Interferon or in the American Harvoni.
Of course, there were side effects, but for the sake of such a result you can endure them. Now I get tested regularly until the virus returns.
Grade: 4
Hepcinat LP was started as soon as the diagnosis was made. My son (he is 21 years old) has not had liver cirrhosis yet, he was lucky. The drug was tolerated without any side effects: slight fatigue, heaviness. The effect came quite quickly, we did not even expect it. The virus has stopped reproducing, the doctor said so, which means hepatitis C has been defeated. We took tests, almost everything was normal. Now we continue treatment with other medications.
Strong combination of substancesGrade: 5
The combination of sofosbuvir and ledipasvir, which make up Heptsinate, turned out to be effective. Before the start of the course, the levels of alt and ast enzymes were high: 68 and 80 units, respectively. Now my alt is 36 units (only 1 higher than normal), and my ast is 30, a truly exemplary indicator. Of course, the treatment did not go smoothly, there were also minor side effects, but for the sake of the result it is worth being patient.
Thanks to the advent of the generic Hepcinat LP, a simplified system of treatment for people with hepatitis C virus has become possible. Its use guarantees much more short term rehabilitation and a simplified treatment system.
Overview of the medicine and features of administration
Hepcinate LP is sold in pharmacies in the form of tablets with a yellow tint, they have an oval shape. On one side of the tablet, covered with glaze, there is the inscription “LP”. One bottle contains 28 of them. In order to absorb moisture, a special silicate gel is placed in the jar. The cover is protective, which prevents accidents involving children.
Hepcinate LP is combined agent. It contains: 0.09 g and 0.4 g of Sofosbuvir.
The components of the medicine, entering the patient’s body, inhibit the work of those enzymes whose action is aimed at the spread and secondary synthesis of the hepatitis C virus.
Included tablets also includes:
- pyrogenic silicon dioxide;
- cellulose;
- magnesium salt of stearic acid;
- croscarmellose sodium;
- copovidone;
- food additive E 172;
- ethylene glycol polymer;
- polyvinyl alcohol powder;
- talc;
- titanium dioxide.
The high effectiveness of the drug is achieved due to the fact that therapeutic work carried out by two active substances at once. According to medical data, Heptsinate LP helps cure 95% of patients from hepatitis C.
After five hours, the maximum concentration is reached in the patient’s body. active ingredients drug. It does not affect oxidation processes in the human body.
Instructions for use of Hepcinate LP states that one tablet of the drug must be taken orally with meals.
If you take this remedy on an empty stomach, the antiviral effect of the drug will not be weakened. Take Hepcinat LP necessary daily set time. Systematicity will help maintain the required amount active substance in the body constantly. The tablets should not be crushed or dissolved in water beforehand.
If the patient discovers that he has missed one dose of the drug, then there is no need to take two tablets per day. next appointment. This can cause poisoning and serious consequences in the form of anaphylactic shock.
For those undergoing treatment with Heptsinate LP for the first time, doctors prescribe a course lasting three months, regardless of whether the patient has cirrhosis of the liver. If the viral load in the patient’s body does not exceed 6 million units/ml, then the duration of therapy is reduced to two months.
If the person has already been treated antiviral drug another type, but this did not produce therapeutic results, then Hepcinate LP is prescribed for 4 months. Those for whom this treatment is secondary and have cirrhosis need to take these tablets systematically for 24 weeks.
Indications and contraindications for use
Hepcinate LP is prescribed to those who have the first genotype of this disease. The outcome of treatment and the possibility of relapse directly depend on several factors:
- stages of the disease;
- presence of diffuse liver disease - cirrhosis;
- the presence of viruses of another type;
- presence of HIV infection.
Contraindications to taking Hepcinat LP include pregnancy, the drug also has a number of limiting factors, these include:
- availability individual intolerance one of the components of the drug;
- lactation period;
- kidney disease;
- age factor – up to 18 years.
According to studies, the presence of impaired heart function can provoke cardiac arrest or deterioration in health. It is prohibited to use Heptsinate LP together with Amiodarone, as this can lead to irreversible consequences. Therefore, before undergoing treatment with this generic drug, you must undergo a complete medical examination and obtain a doctor's opinion.
Patients who take beta-blockers, drugs that stimulate cardiac activity and those who have severe liver disease should consult a specialist before taking Hepcinat LP, as adverse reactions are possible.
Poisoning of the body toxic substances manifests itself in the form of absent-mindedness, shortness of breath, lack of physical strength, migraine, fatigue, apathy, lethargy in the body and painful sensations in the area of the heart.
If these signs occur, you should immediately consult a doctor; he will determine what is causing this reaction in the body. He will prescribe a drug from which the component intolerable by the body is excluded.
Side effects and interactions with other drugs
Side effects of Heptsinate LP manifest themselves in the form of sharp reactions of the body, causing frequent complaints from patients about their well-being. TO side effects include:
- migraine and apathy;
- nausea and vomiting;
- diarrhea;
- sleep disturbance.
Those taking Hepcinat LP may also experience an increase in bilirubin and lipase, which is asymptomatic.
Compatibility of Hepcinate LP with drugs, containing , is absent, that is, their simultaneous use is prohibited. Antacids, H2 receptor antagonists, inhibitors proton pump help reduce the amount of Ledipasvir.
P-glycoprotein stimulants may also reduce the concentration of Ledipasvir and Sofosbuvir in the body, which will reduce the effectiveness of therapy.
Therefore, you should not combine P-glycoprotein and Hepcinate LP.
So, Hepcinate is modern means, developed for the treatment of the first and fourth genotypes of the hepatitis C virus. There is no need to combine this drug with Interferon or Ribavirin. But we must remember that so serious drug can only be prescribed by the attending physician.