Lee Zodak. Composition and forms
Just six months ago, the pediatrician always prescribed during colds or before vaccinations the drugs "Fenistil", "Suprastin". Now you hear more and more often about the medications “Cetirizine” or “Zodak” (drops). and adults in some cases gives different recommendations. Let's take a closer look at them.
The drug is a clear or light yellow solution in a dark bottle and cardboard packaging. These drops are prescribed when a child or adult:
- permanent or seasonal conjunctivitis;
- allergic rhinitis;
- allergic skin rashes;
- Quincke's edema;
- hives.
Dosage for children and adults
The drug for children and adults requires diluting it in a small amount of water, for example, a tablespoon, before use. It is better for children to drink it with sweet compote or tea.
Twice a day should be used:
- five drops for children from one to six years old;
- ten drops for preschoolers and younger schoolchildren(six to twelve years).
Take no more than twenty drops once, preferably in the evening:
- children over twelve years old;
- adults.
These data are written in the instructions, but the number of drops is prescribed by the doctor, who takes into account individual characteristics patient and severity of the disease.
The medication should not be given to children under one year of age, pregnant or nursing mothers. Do not take without a doctor for people with chronic renal failure and the elderly. This is due to the fact that cetirizine in this category of people is eliminated not after five to ten hours, but after fifteen to thirty hours.
The drug "Zodak" (drops): instructions. For children and adults with kidney and liver disease
If a person has kidney failure, then the intake of drops is halved. For example, one-year-old babies and children under six years old, two and a half drops, schoolchildren under twelve years old, five drops, and adolescents and adults - no more than ten drops. If you have liver disease, you should not take more than ten drops per day. Elderly people with healthy kidneys You can leave the dose recommended in the instructions (twenty drops). However, please note that the number of days of admission of this product prescribed by the doctor.
The drug "Zodak" (drops for children) is stored in the refrigerator for about three years. The price of the drug is no more than two hundred rubles. So this is the most economical medicine. Additionally, these drops can be given to people with diabetes mellitus, since they do not contain sugar. But during treatment you should not drink alcohol, theophylline and drugs that depress the central nervous system.
The drug "Zodak" (drops for children): instructions for the behavior of adults in case of overdose
At self-treatment or ignoring doctor's orders, an overdose may occur. Characteristic symptoms (severe headaches, tachycardia, fast fatiguability, irritability, drowsiness, urinary retention, lethargy) may appear with the consumption of fifty milligrams (about one hundred drops) already on the day of administration. In this case call ambulance. Specialists will rinse the stomach and prescribe Do not leave the product in open access if there are children in the house.
Thus, without a doctor’s prescription, do not buy the antiallergic drug “Zodak” (drops) in pharmacies. The instructions for children and adults describe a number of side effects from digestion, nervous system. Allergic individual reactions may occur.
Allergies, no matter what caused them, are always a problem. Skin itching, rash, swelling and even irritation of the mucous membranes are all characteristic reactions of the body that cause not only discomfort, but can also cause significant harm to health. Therefore, at the first allergic manifestations, it is necessary to immediately start taking antihistamines, such as Zodak drops. This drug will reduce symptoms within 30-120 minutes and significantly improve the patient’s condition.
Composition and pharmacological action
The only active substance of the drug is cetirizine dihydrochloride, which acts as a blocker of human peripheral receptors. It is this component of the drug that prevents the release of histamines from mast cells and basophils, and also reduces the migration of eosinophils. Povidone, corn starch, talc, lactose manohydrate, magnesium stearate, titanium dioxide, dimethicone emulsion and hydroxypropyl methylcellulose are used as auxiliary inactive components of the drug. Despite the fact that the drug does not have a sedative effect, it is necessary to take only the doses of Zodak (drops) recommended by the doctor. The instructions for use also contain detailed information about who can drink them and in what quantities. The medicine does not affect the amount of food absorption, but the rate of absorption of cetirizine is significantly reduced. The concentration of the active substance in the blood plasma reaches its maximum level after 0.5-1.5 hours. But it is worth noting that the cumulative effect, even at the maximum dose, is not observed over a long course of treatment, and after 9-10 hours the half-life process of cetirizine occurs. This pharmacological effect is achieved due to the fact that the main substance is slightly subject to metabolic transformation when passing through the body's natural filter - the liver. And as studies have shown, 2/3 of cetirizine is excreted in the urine in unchanged form.
Indications for use
Due to the extensive action of the drug, the scope of its use is limited not only to the prevention of allergies, but also to the treatment of even severe cases; in such situations, doctors often prescribe Zodak (drops). Instructions for use confirm that they are used for the treatment of urticaria and itching of various origins, including particularly difficult cases accompanied by fever. This medicine is also prescribed for patients suffering from seasonal allergies and chronic rhinitis. Often the body’s defensive reaction manifests itself in the form of conjunctivitis, which experts recommend to cope with using the drug “Zodak”. In order to prevent and relieve swelling of the upper respiratory tract This medication can be prescribed for acute respiratory viral infections and acute respiratory infections.
Method of use of the drug
Before considering questions about taking and dosing the Zodak medication, it should be noted that all its forms - syrup, drops and tablets - have identical pharmacological effects. However, it is precisely concentrated solution, packaged in a convenient glass package with a dispenser, is popular among patients. The increased demand for this form is due to the fact that the drops can be taken by everyone, regardless of age. Thus, in pediatrics for children from birth to 2 years of age, it is recommended daily dose is 2.5 mg, which is equivalent to ten drops, divided into two equal doses. For older children aged 2 to 6 years, with mild allergic reactions, the dose should not be increased, but in difficult cases it can be taken once a day. For younger and middle children school age up to 12 years of age, Zodak for allergies should be taken 10 drops twice a day or 10 mg (20 drops) daily. For adolescents over the age of twelve and adults, the dose of medication is 1 ml, which is equal to 20 drops.
How to take medicine for people with health problems
Patients diagnosed with moderate and serious violation renal function, this selective peripheral receptor blocker should be used with extreme caution and only as directed by a physician. It is the doctor who, in each individual case, must calculate an acceptable therapeutic dose for the treatment of allergies. In cases of minor renal failure When the organ filtration rate, such as creatine clearance (CLCR), is 50-79 ml/min, there is no need to adjust the medication. However, when mild stage disorders (CLCR≤ 30-49 ml/min), the dosage should be halved, since with such a disease the rate of drug elimination is significantly reduced. For those patients who suffer from severe renal dysfunction with a filtration rate of less than 30 ml per minute, the instructions for use recommend taking Zodak (drops) in an amount of no more than 10 mg once every two days. Treatment of allergies during the thermal stage of this disease is strictly prohibited.
Drug overdose
Despite the fact that the drug "Zodak" in recommended doses has a weak anticholinergic effect, in cases of overdose it can cause enormous harm to health. This manifestation is especially dangerous for elderly patients and people who have problems with the heart and blood vessels, with gastrointestinal tract, since as a result the heartbeat slows down and intestinal motility increases. From the hepatobiliary system, an increase in the activity of liver enzymes and bilirubin content can be expected. In some cases of overdose, a number of other side effects have been recorded, such as difficulty urinating, eye accommodation and a feeling of dry mouth. A reaction to an increased dose of Zodak from the peripheral and central nervous systems may include drowsiness, dizziness, fatigue and severe headaches.
Who is contraindicated for Zodak?
The use of this drug by patients with hypersensitivity to any component of the drug. Such therapy can aggravate the patient’s condition and cause irreparable harm to his health; it is important to remember this before you start using Zodak (drops). The instructions for use also contain information that it is not recommended to use it during pregnancy and breastfeeding. This warning is due to the peculiarity of the active substance of the drug, which is excreted from the body unchanged. Therefore, it is almost impossible to determine the dose of the drug that passes through mother’s milk to the baby. It is also strictly forbidden to take Zodak for patients with acute renal failure.
Interaction of the drug with other drugs
According to the results clinical trials, cetirizine without reduction therapeutic effect can be used with medicines, based on cimetidine, ketocanazole, pseudoephedrine, erythromycin and azithromycin. Slight decrease Kidney filtration is observed only in patients who combine the drug with the systematic use of a large dose of theophylline. Moreover, after completing the course of such treatment, the indicators return to normal without medication assistance. No adverse clinically significant interactions of the Zodak drug with other medications have been identified. However, before you start taking this antihistamine in combination with other medications, you must consult your doctor.
Precautionary measures
As shown clinical trials, no significant interaction between the drug and small doses of alcohol was identified. However, we should not forget about the individuality of the body, which may react inadequately to such a combination. Therefore, it is better to refrain from drinking alcoholic beverages while taking an antihistamine. Extra caution should also be observed by people taking the drug Zodak when working at height, driving vehicles and servicing machinery.
Zodak belongs to the group of second-generation antiallergic drugs that have a prolonging effect. The main component of the drug is cetirizine dihydrochloride, which does not cause a sedative state. This medicine eliminates any types and degrees of allergic manifestations, while suppressing them even further cellular level. Zodak is prescribed to eliminate itching, fever, urticaria and others characteristic symptoms allergies. The product is very effective in combating the manifestations of seasonal, year-round allergies, especially during the onset of allergic rhinitis and conjunctivitis.1. Pharmacological action
A second-generation antiallergic drug with a long-lasting therapeutic effect that does not cause depression of the nervous system, including drowsiness. The mechanism of action of Zodak is directly related to the selective blocking of histamine receptors, the main substance that causes all allergic reactions. Zodak affects both early and late stage allergies. Zodak does not form accumulations in the body and almost completely binds to blood plasma proteins. Its maximum concentration occurs 1-1.5 hours after taking the drug in any form. Most of Zodak is excreted unchanged by the kidneys.
2. indications for use
- Seasonal or year-round manifestations allergic rhinitis or ;
- And itchy skin of various origins.
3. Method of application
Zodak is taken regardless of food intake. The dosage depends on its form and the age of the patient.
- Patients aged 6 to 12 years - half a tablet 2 times a day;
- Patients over 12 years of age and adults - 1 tablet once.
4. Side effects
- Disorders of the nervous system (drowsiness, dizziness, headache, fatigue);
- Liver dysfunction (increased activity of liver enzymes, increased bilirubin concentration).
5. Contraindications
For all dosage forms of the drug:
- Pregnancy and lactation;
- Hypersensitivity to the drug and its components;
- Individual intolerance to the drug Zodak and its components;
- Functional kidney failure high degree gravity.
6. During pregnancy and lactation
Zodak is contraindicated throughout pregnancy and lactation. If necessary, its use during breastfeeding, it is stopped throughout the treatment until the drug is completely eliminated from the body.
7. Interaction with other drugs
Not described
8. Overdose
Various disorders of the nervous system, changes heart rate, urinary retention. There is no specific antidote. If the described symptoms occur, the patient undergoes gastric lavage and is prescribed medication to eliminate them. Mechanical blood purification (dialysis) does not produce results.
9. Release form
Tablets, 10 mg - 7, 10, 30, 60, 90 or 100 pcs.
10. Storage conditions
Zodak should be stored away from light at a temperature not exceeding room temperature.
11. Composition
1 tablet:
- cetirizine dihydrochloride - 10 mg;
- Excipients: lactose monohydrate, corn starch, povidone, magnesium stearate.
12. Conditions for dispensing from pharmacies
The drug is available without a prescription.Zodak for allergies
Zodak is effective means against allergies. Instructions for use of the medicine Zodak indicate that it contains the active substance - cetirizine. It is due to this substance that the healing effect.
The drug is a histamine antagonist, which provokes allergic manifestations. Zodak has a pronounced anti-allergic effect, preventing the occurrence of allergic manifestations. If they do occur, the drug helps alleviate their course.
An antihistamine eliminates itching and relieves spasms smooth muscle, reduces vascular permeability, due to which swelling goes away. Practically does not cause drowsiness.
Zodak helps to cope with such allergic diseases How:
- Quincke's edema;
- Hives;
- Hay fever;
- Itchy skin rashes;
- Allergic rhinitis and conjunctivitis.
Despite positive effect with allergies, Zodak has a number of contraindications, and with incorrect reception may cause Negative consequences, so it must be prescribed by a doctor. The specialist will select the dosage and duration of treatment.
The drug is available in tablets, drops and syrup, which is intended for the treatment of children.
On average, the following dosages of an antihistamine are prescribed:
- Drops. Children from 12 months to 2 years are prescribed to take 2.5 mg twice a day, contained in 5 drops. It is recommended to give a child from 2 to 6 years 10 drops once or 5 twice a day. From 6 years to 12 years, 20 drops are given once or 10 drops in the morning and evening. Adults and children over 12 are prescribed 20 drops once, preferably in the evening;
- Pills. Children from 6 to 12 years old are given 1 tablet containing 10 mg active substance once or prescribe half a tablet (5 mg) twice a day. Adults and children over 12 years of age take 1 tablet 1 time per day;
- In the form of syrup, from 2 to 6 years old, 1 scoop is given once or half a scoop twice a day. A child from 6 to 12 years old is prescribed 2 scoops once or 1 scoop twice a day. Adults and children over 12 years of age take 2 scoops once.
Which is better: Zodac or Zyrtec
Both drugs are based on the same substance - cetirizine, and therefore have similar indications, contraindications and side effects. However, antihistamines also have differences, namely:
- Country of Origin;
- Price. Zyrtec costs more than Zodac;
- Composition of excipients. Therefore, Zyrtec may be more suitable for some people, and Zodak for others.
In addition, Zyrtec is original drug, having a higher quality composition and numerous safety tests. Zodak is its generic, so it is slightly inferior to Zyrtec.
It is difficult to say which drug is better, because the therapeutic effect is achieved due to the same substance and both drugs are considered effective. However for the treatment of children it is better to choose Zyrtec because of its higher quality composition.
Zodak or Suprastin
Both drugs are classified as antihistamines. However, Suprastin is an older 1st generation drug, and Zodak is a 2nd generation drug.
The instructions for the Zodak indicate that it active substance is cetirizine, and Suprastina is chloropyramine. So which of these drugs is better?
Since Suprastin belongs to the first generation, it causes drowsiness and reduces concentration, and also more often causes side effects.
It is difficult to say which drug is better, because they have completely different main substances. The choice of antihistamine will depend on the complexity of the disease.
For example, Suprastin has an injection solution that acts much faster than Zodak drops and tablets, so it is better suited for first aid. Zodak, on the other hand, has a milder effect, while also effectively coping with allergies.
How many days to take Zodak
The duration of treatment with Zodak depends on the severity of the disease, the severity of allergic manifestations, the age of the person, as well as many other factors.
Therefore, the doctor will tell you exactly how long the drug can be used, because the course can vary from several days (in the case of acute forms), to several weeks or even months (in case of chronic course diseases). At long-term use breaks are required.
On average at acute forms the course of treatment is about 5-7 days.
Zodak for chickenpox in children
The chickenpox rash is always accompanied by severe and unbearable itching. Zodac will help alleviate the condition of a child or adult by eliminating itching.
The drug will also reduce the swelling and redness of itchy pimples and help speed up the drying process of their watery forms.
It has a quick and long-lasting effect, practically does not cause drowsiness and will help alleviate chickenpox in adults and children starting from 12 months.
The dosage for this disease is usually standard; a more precise concentration will be determined by a doctor who will assess the severity of the disease and the severity of itching.
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* Instructions for medical use for the drug Zodak tablets is published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, YOU MUST CONSULT WITH A SPECIALIST
Antiallergic drug, histamine H1 receptor blocker.Drug: ZODAK
Price: 201 RUR Buy
Active substance: cetirizine
ATX code: R06AE07
KFG: Histamine H1 receptor blocker. Antiallergic drug
Reg. number: LS-000433
Registration date: 07/01/05
Owner reg. cred.: ZENTIVA a.s. (Czech Republic)
DOSAGE FORM, COMPOSITION AND PACKAGING
Drops for oral administration transparent, colorless to light yellow.
Excipients: methylparaben, propylparaben, glycerol, propylene glycol, sodium saccharin, sodium acetate, glacial acetic acid, purified water.
20 ml - dark glass bottles (1) with a dropper cap - cardboard packs.
Syrup transparent, colorless to light yellow.
Excipients: methylparaben, propylparaben, glycerol, propylene glycol, liquid sorbitol, sodium saccharin, sodium acetate, glacial acetic acid, banana flavor, purified water.
100 ml - dark glass bottles (1) complete with a measuring spoon - cardboard packs.
The description of the drug is based on the officially approved instructions for use.
PHARMACHOLOGIC EFFECT
Antiallergic drug, histamine H1 receptor blocker. Cetirizine belongs to the group of competitive histamine antagonists. It has a pronounced antiallergic effect, prevents the development and facilitates the course of allergic reactions. Has antipruritic and antiexudative effect. Affects early stage allergic reactions, and also reduces the migration of inflammatory cells; inhibits the release of mediators involved in a late allergic reaction. Reduces capillary permeability, prevents the development of tissue edema, relieves spasm of smooth muscles. Eliminates skin reaction to the introduction of histamine, specific allergens, as well as cooling (for cold urticaria).
It has virtually no anticholinergic and antiserotonin effects.
IN therapeutic doses has practically no effect sedative effect. During the course of treatment, tolerance does not develop.
The effect of the drug begins after 20 minutes (in 50% of patients) or after 1 hour (in 95% of patients) and lasts for 24 hours.
PHARMACOKINETICS
Suction
After oral administration, cetirizine is quickly and almost completely absorbed from the gastrointestinal tract. Cmax in blood plasma is determined after approximately 30-60 minutes. Food intake does not have a significant effect on the amount of absorption, but in this case the rate of absorption is slightly reduced.
Distribution
The binding of cetirizine to plasma proteins is about 93%. The Vd value is low – 0.5 l/kg. Cetirizine does not penetrate into the cell. Does not penetrate the BBB.
Metabolism
Cetirizine is poorly metabolized in the liver to form an inactive metabolite.
With 10-day use at a dose of 10 mg, no accumulation is observed.
Removal
After a single dose, T1/2 is about 10 hours. About 70% is excreted by the kidneys, mainly unchanged. The systemic clearance is about 54 ml/min.
Pharmacokinetics in special clinical situations
In children aged 2 to 12 years, T1/2 decreases to 5-6 hours.
In case of impaired renal function (creatinine clearance from 11 to 31 ml/min) and in patients on hemodialysis (creatinine clearance less than 7 ml/min), T1/2 increases by 3 times, clearance decreases by 70%.
On the background chronic diseases and in elderly patients there is an increase in T1/2 by 50% and a decrease in clearance by 40%.
Cetirizine is not excreted by hemodialysis.
INDICATIONS
Seasonal and year-round allergic rhinitis and conjunctivitis;
Itchy allergic dermatoses;
Hay fever (hay fever);
Urticaria (including chronic idiopathic);
Quincke's edema.
DOSING REGIME
The drug is prescribed orally, regardless of food intake. Before taking, dissolve the drops in water.
Adults and children over 12 years old- 10 mg of cetirizine (20 drops or 2 scoops of syrup) 1 time/day, daily, preferably in the evening.
Children from 6 to 12 years old- 10 mg of cetirizine (20 drops or 2 measuring spoons of syrup) 1 time per day or 5 mg of cetirizine (10 drops or 1 measuring spoon) 2 times a day - morning and evening.
Children from 2 to 6 years old- 5 mg of cetirizine (10 drops or 1 measuring spoon of syrup) 1 time / day or 2.5 mg of cetirizine (5 drops or 1/2 measuring spoon of syrup) 2 times / day - morning and evening.
Children from 1 to 2 years old- 2.5 mg (5 drops) 2 times/day.
At renal failure the recommended dose should be reduced by 2 times.
At liver dysfunction the dose should be selected individually, reducing it to 5 mg/day or less, with extreme caution with simultaneous renal failure.
Elderly patients with normal function renal dose adjustment is not required.
Rules for using a bottle with a safety cap
The bottle is closed with a cap with a safety device that prevents children from opening it. The bottle opens by pressing the cap firmly down and then unscrewing it counterclockwise. After use, the bottle cap must be screwed on tightly again.
SIDE EFFECT
From the digestive system: dry mouth, dyspepsia.
From the side of the central nervous system: headache, drowsiness, fatigue, dizziness, agitation, migraine.
Allergic reactions: skin rash, angioedema, urticaria, skin itching.
The drug is usually well tolerated. Side effects occur rarely and are transient.
CONTRAINDICATIONS
Pregnancy;
Lactation period;
Children under 1 year of age (drops for oral administration);
Children under 2 years of age (syrup);
Hypersensitivity to the components of the drug.
WITH caution used for chronic renal failure of moderate and severe severity (correction of the dosage regimen is required), in elderly patients (possible reduction glomerular filtration).
PREGNANCY AND LACTATION
The drug is contraindicated during pregnancy and lactation.
SPECIAL INSTRUCTIONS
Instructions for patients with diabetes mellitus
Drops for oral administration do not contain sugar (saccharin is used as a sweetener), so this dosage form can be prescribed to patients with diabetes.
10 ml of syrup (2 scoops) contains 3 g of sorbitol, which corresponds to 0.25 XE.
Impact on the ability to drive vehicles and operate machinery
During the treatment period, it is necessary to refrain from potentially active activities dangerous species activities requiring increased concentration attention and speed of psychomotor reactions.
OVERDOSE
Symptoms: possible drowsiness, lethargy, weakness, headache, tachycardia, increased irritability, urinary retention, fatigue (more often when taking cetirizine at a dose of 50 mg/day).
Treatment: gastric lavage, purpose activated carbon, carrying out symptomatic therapy. A specific antidote has not been identified. Hemodialysis is ineffective.
DRUG INTERACTIONS
No clinically significant interactions of cetirizine with other drugs have been established.
Combined use with theophylline (400 mg/day) leads to a decrease in the overall clearance of cetirizine (theophylline kinetics does not change).
CONDITIONS OF VACATION FROM PHARMACIES
The drug is approved for use as a means of OTC.
CONDITIONS AND DURATION OF STORAGE
The drug should be stored out of the reach of children at a temperature below 25°C. The shelf life of the drug in the form of drops for oral administration is 2 years, in the form of syrup – 3 years.
A drug called Zodak is presented on the pharmaceutical market in the form of drops and tablets - the instructions for use say that the product is effective against allergies. The advantage of the medication is that it has an antisedative effect; when you take it, you don’t feel sleepy. The drug helps to actively fight allergic manifestations such as itching and rashes.
What is Zodak
The 2nd generation drug – Zodak has a prolonged effect, due to which the duration of action of the main component increases. The medication shown in the photo eliminates allergy symptoms due to the active substance - a selective blocker of peripheral H1 receptors. Indicated for use during exacerbation of seasonal allergies, as well as chronic diseases of this type. Even if you take the drug for a long time, there will be no problems with the central nervous system (drowsiness or depressive state).
Composition of the Zodak
The main active ingredient is cetirizine dihydrochloride, which acts against negative reaction body to irritants in early (histamine-dependent) and late cell phase. Under the influence of the substance, histamines undergo a process of release from various cells (mast cells, basophils, etc.). Zodak - instructions for use describes the composition different forms release - the drug is popular, here is its composition:
| Release form | Additional components |
|---|---|
|
|
| Pills |
|
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Release form
Zodak is produced in 3 different types drug: tablets, drops, syrup. Zodak drops or syrup form are more suitable for children. The latter option has a banana smell and taste, which makes its intake pleasant and healthy. Adults can choose Zodak tablets, which are more practical: a person, knowing in advance that he may be exposed to an irritant, can take the medicine in any environment. Below is a table of release forms and their features:
Zodak - indications for use
The drug is effective against seasonal allergies, in the treatment of diseases with established diagnosis, including manifestations of allergic reactions. The drug is taken at the first symptoms associated with the body's response to irritants of various origins. The doctor prescribes Zodak for symptomatic therapy, for diseases such as conjunctivitis, year-round rhinitis allergic nature. List of symptoms and diseases that Zodak helps with:
- urticaria, normal or with fever (chronic idiopathic urticaria);
- swelling of the mucous membrane;
- chronic or seasonal allergies;
- sneezing;
- allergy to flowering plants (hay fever);
- cough;
- itchy dermatoses allergic origin;
- Quincke's edema.
For children
Children over 6 years of age are allowed to take antiallergic drugs in the form of tablets. Taking such a remedy as Zodak is strictly prohibited for children under one year of age. Information about the prohibition for newborns is indicated as a contraindication to the medication. If there is an urgent need to take a drug with a similar effect, the doctor prescribes the child an analogue with a similar active ingredient, which is approved for children under one year of age. A child after one year can take drops or syrup in the dosages indicated in the instructions or prescribed by a doctor.
For adults
At allergic symptoms an allergist can prescribe Zodak for adults. The convenient form of the drug in the form of tablets does not cause discomfort throughout the day. You can take 1 tablet with a glass of water anywhere, this will help get rid of food or other allergies. Adult patients should remember that the drug should not be combined with alcoholic drinks. Zodak does not work after drinking alcohol.
Is Zodak possible during pregnancy?
Zodak should not be taken during pregnancy; the drug is prohibited during lactation and pregnancy. The antiallergic drug Zodak is an antihistamine, and in the first trimester, taking any drugs with a substance that suppresses the effect of free histamine is prohibited. After the onset of the second trimester in severe cases the doctor may prescribe Zodak. The danger of taking medication is that any antihistamines negatively affect the fetus.
How does Zodak work?
Histamine is a biogenic substance that is involved in the development of reactions to allergens. Active ingredient inhibits the release of histamine due to its blocking properties nerve endings(H1 receptors). Zodak is most effective on initial stage interactions with the allergen. The medicine reduces the permeability of capillaries (small blood vessels), which protects against the development of bronchospasm. Doctors advise taking Zodak for allergies in advance, at the first suspicion of penetration of an irritant.
Zodak drops - instructions for use for children
A children's allergist or pediatrician can reliably determine the cause of the child's body's hypersensitivity in response to irritants. The specialist prescribes the medicine in the form of drops in a convenient bottle, which will prevent children from spilling the medicine. One bottle contains 10 mg of the active substance - cetirizine, under the influence of which the allergy chains are blocked and the symptoms disappear. Zodak's instructions for use state that the medication should be dissolved in water (5 ml) and drunk. The product has the following effects:
- antiexudative;
- decongestant;
- antipruritic.
How long can a child take Zodak?
The instructions for use say how many days children can take Zodak. From general recommendations It can be emphasized that you should take the medicine at the same time every day, trying not to miss a dose. The duration depends on the form of release and concomitant disease. The instructions for use of the medicine contain a table in which you can find out the course of treatment. Therapy can last from 5 to 7 days, in some cases up to a year, with breaks between doses.
How to take Zodak drops for children
You can take the product regardless of meals. The required dose of the drug is dissolved in water. Zodak is not used for newborns. Parents facing allergic reactions children after one year are interested in the question of how many drops of Zodak to give to a child: a doctor can answer this. After reading the information about Zodak drops - instructions for use are available - you can find out that the correct dose and time of taking the drug depends on the age of the child:
- From 1 to 2 years: 5 drops twice a day (2.5 mg each).
- From 2 to 6 years: 10 drops 1 time (5 mg each) or 5 drops 2 times (2.5 mg each).
- From 6 to 12 years: 20 drops per 24 hours (10 mg each) or 10 drops (5 mg each) twice.
- Over 12 years: 20 drops (10 mg each), evening.
Zodak - instructions for use for adults
Eating does not affect the absorption of the drug into the body. If the instructions for use say that the product is taken once a day, then it is better in the evening. When taking the drug twice a day, it is consumed at 9 am and 9 pm, at equal intervals. Medicine in tablet form should not be crushed, but should be drunk with big amount water. If a dose is missed, it cannot be combined with a new one. The instructions for use of Zodak state that patients with impaired renal and liver function should take a reduced amount.
How to take Zodak for adults
The three forms of the medicine must be taken differently due to the fact that the concentration of the substance in the tablets, syrup or drops is not the same. After administration, the drug begins to act after 20 minutes. After 60 minutes, the highest effect occurs; 0.3% cetirizine is bound to blood proteins. The Zodak's annotation states that the duration healing properties lasts 24 hours. Due to these features of the drug, when taking it, you must refrain from driving a car and doing things that require concentration. The instructions for use indicate the following dosage of Zodak for adults:
- tablets: 1 dose, 1 tablet. (10 mg/day);
- drops: 1 dose of 20 drops (10 mg);
- syrup: 1 dose, 2 measuring spoons.
Side effects
Zodak - instructions for use states that in case of overdose there is a development side effects– in most cases well tolerated by patients. Rare side effects are observed, but they are transient. If any of the following signs of overdose occur, you should rinse your stomach, take activated charcoal, and symptomatic therapy. Instructions for use indicate the following side effects of Zodak:
- skin itching;
- hives;
- angioedema;
- rash;
- dyspepsia;
- problems with digestive system;
- dry mouth;
- sedation or drowsiness;
- headache;
- migraine;
- increased fatigue;
- excitation;
- dizziness.
Contraindications
The shelf life of an open bottle is two weeks. The drug is used exclusively under the supervision of a physician and with great caution for chronic renal failure of moderate to severe severity. Dosage adjustment is required depending on creatinine clearance. If the patient is elderly, then glomerular filtration may decrease when taken. In addition to pregnancy and breastfeeding, there are other Zodak contraindications:
- sensitivity to the components of the drug;
- drops cannot be used for infants, syrup for up to 2 years, and tablets for up to 6 years;
- alcohol intake (lack of compatibility);
- taking drugs with a depressant effect on the central nervous system.
- non-allergic cough;
- renal dysfunction;
- serious illnesses liver.
Zodak price
Before buying the drug, you should consult a doctor who will prescribe the dosage according to the instructions. How much does Zodak cost? The price depends on the manufacturer and place of purchase in Moscow or St. Petersburg. Can be purchased at pharmacy kiosk or order from an online pharmacy with delivery at a reduced cost. Table approximate prices on antihistamine against allergies:
Analogues of Zodak
Substitutes for any drug are divided into 2 types: absolute and relative. The first ones are those that contain cetirizine dihydrochloride. When looking for Zodak analogues, you should pay attention to the content (dose) active component. Be sure to read the instructions for use. The same components in ointments and tablets do not mean an identical method of use. Relative substitutes are similar to this medicine in their mechanism of action. Absolute analogues include the following drug names:
- Letizen;
- Zyrtec;
- Parpazin;
- Cetrin;
- Allertek;
- Zintset;
- Alerza.
Among the relative and cheap analogues are:
- Nasonex;
- Tavegil;
- Avamis;
- Suprastin;
- Vibrocil;
- Galazolin;
- Nazivin;
- Tizin.
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