Mexidol instructions for use intramuscular injections. Instructions for the use of Mexidol tablets and injections

Description and use of the drug

Mexidol is part of a group of drugs with antioxidant properties.
One of their forms of production is a solution for intramuscular or intravenous administration: transparent, can be completely colorless, or with a slightly cloudy tint. Main chemical element is ethylmethylhydroxypyridine succinate. Pharmacological effects Mexidol injections have the following properties:

It has membrane-protective and antihypoxic, as well as proconvulsant and nootropic effects.
Manifoldly increases a person's resistance to stress.
. Resistance to the negative influence of environmental factors also increases.
. Excellent ability to overcome various oxygen-dependent pathologies: shock of various natures, hypoxia, vascular accidents, tissue ischemia, intoxication alcoholic products and antipsychotic drugs.
. There is a significant improvement in cerebral metabolism and blood supply to all tissues.
. The aggregative and rheological parameters of blood elements improve.
. The membranes of blood elements are stabilized.
. There is a significant lipid-lowering effect.

The main positive mechanism of action of Mexidol in injections is associated with its undoubted antioxidant and antihypoxic effects, as well as a membrane-stabilizing effect. The drug improves the activity of superoxide dismutase, inhibits lipid oxidation, reduces membrane viscosity and increases its fluidity, and also modulates the activity of membrane-binding enzymes. Mexidol in injections stabilizes metabolic processes in ischemically disadvantaged areas of the tissues of the heart and brain, improves electrical contractility and activity of the heart muscle, increases ganglion activity of nitrates.

Indications for use of Mexidol in ampoules

Acute brain catastrophes.
. Consequences of various cranial - brain injuries.
. All kinds of encephalopathy.
. Vegetative syndrome - vascular insufficiency.
. Cognitive decline caused by atherosclerotic plaques.
. As part of a complex for ischemic conditions.
. Open angle glaucoma.
. Relief of withdrawal syndromes
. At acute intoxication antipsychotic drugs.

Mexidol injections are contraindicated for diseases such as:

Acute renal and liver failure.
Increased individual susceptibility to ethylmethylhydroxypyridine succinate.

Mexidol in ampoules for course therapy is prescribed only by a specialist. Strictly controlled observations of its use in pregnant women, during lactation, as well as in children have not been carried out - Mexidol in injections has not been carried out, therefore, in the listed cases, they try to avoid it.

Cost of the drug in pharmacies: Mexidol ampoules 5%, 5 ml, 5 pcs. price 420 rubles, price Mexidol ampoules 5%, 5 ml, 20 pcs. 1600 rubles, price Mexidol ampoules 5%, 2 ml, 50 pcs. 2050 rubles. Mexidol analogs prices: Cecard ampoules 250 mg. 5 ml, 5 pcs. 240 rubles, Mexicor ampoules 50 mg/ml 2 ml, 10 pcs. 325 rubles.

Analogues of Mexidol, which are similar in composition and action, are such drugs as: Mexiprim, Mexicor, Mexidant, Mexifin, Cerecard, Neurox, Medomexi, etc.

Official instructions for use Mexidol injections

Reviews and comments

Oksana

Mexidol injections are in demand not only among older people, but also among young people. I’m thirty-something, but I already have problems with the blood vessels in my head and I’ve begun to react to changes in weather very often. I contacted a specialist and received a referral for a course of Mexidol injections. I carefully read the instructions for using Mexidol in injections and learned that I would then need to take Mexidol in tablets. She did everything conscientiously, although she did not feel any negative sensations either from Mexidol injections or from Mexidol tablets. The product has helped greatly, migraine pains have become less frequent. Reviews from Meksidal were the most favorable.

Andrey V.

After forty years, I began to feel tired, blurred vision, and frequent headaches. I didn’t want to go to the doctor, they would consider me completely sick, or they would tell me to work. I turned to the Internet in search of medical forums. I came across a description of the action of Mexidol. I carefully read the instructions for Mexidol intramuscular injections, where, by the way, the indications for use are detailed. I looked for analogues of Mexidol in injections, but from reviews I learned that Mexidol in injections was still more effective. After the course, I really felt a surge of strength, my vision gradually improved, I stopped getting tired, and I even began to sleep better. In general, reviews of Mexidol have been good.

Catherine

I had to deal with the unpleasant sensations of dizziness and fatigue, at work I stopped being able to do everything, and there were complaints from my superiors. Passed medical checkup To be honest, I thought the hemoglobin had dropped again, this has happened before. But lab tests were normal. The blood vessels in the head were checked and it turned out that there were abnormalities. The specialist prescribed the drug Mexidol intramuscular injections, explained why it was prescribed, and what possible side effects were possible. Added to it complex vitamins, advised me to walk outside more often and get enough sleep regularly. A month later I felt completely healthy person. Mexidol reviews in ampoules are the best. Now I recommend similar courses to my friends, of course, after consultation with a specialist.

Valery

I have in Lately began to experience nervousness, irritability and headache, especially in the temple area. A friend advised me to inject the medicine Mexidol, but I don’t like injections, so I once again asked a neurologist whether Mexidol tablets or injections are better, the doctor advised injections as the effect will be faster and stronger. The course of treatment was completed in 10 days, during the injections there was slight drowsiness and lightness in the body and head. In general, the reviews for Mexidol injections were positive, but I don’t recommend injecting them all the time, because... addiction occurs.

Mexidol injections can help with different situations related to problems nervous system, and not only. The list of indications for use is quite wide, but the decision on use is made solely by the doctor.

Composition, release form and packaging

Mexidol is produced both in tablets and in the form of a solution for injections. The last one looks like clear liquid, sealed in ampoules of 2 or 5 ml. The package usually contains five containers.

Each milliliter of medicine contains:

  • ethylmethylhydroxypyridine succinate (medicinal component) – 50 mg;
  • sodium metabisulfite;
  • water for injections.

This is a very popular drug. Especially for those who had to struggle with abnormalities in the functioning of the brain, including stroke survivors. However, the medicine has proven itself not only in neurology, but also in other areas of medicine, from psychiatry to surgery.

Pharmacological action and pharmacodynamics

Mexidol has phenomenal biological activity.

He:

  • activates metabolism;
  • improves the functioning of cell membranes;
  • normalizes cholesterol levels;
  • reduces symptoms of poisoning;
  • relieves cramps;
  • restores the electrical activity of the heart;
  • successfully fights anxiety and panic attacks;
  • helps to resist stress;
  • improves memory and ability to concentrate;
  • normalizes blood supply to the brain;
  • stops processes negative influence lack of oxygen affects the body.

The medicine quickly penetrates the body cellular level, gives the strength to withstand situations caused by a lack of oxygen in the blood, including ischemia, hypoxia, and oxygen deficiency in the brain.

In addition, Mexidol is able to remove alcohol toxins and improve the poor health of a person suffering from withdrawal syndrome (the so-called complex of pathologies that arise in a chronic alcoholic due to sharp decline usual dose of alcohol or refusal from it). It also helps during operations for purulent processes in the peritoneum and helps with neurotic and neurotic-like conditions.

The introduction of "Mexidol" inhibits the formation of free radicals and strengthens the membranes of red blood cells, does not allow platelets to stick together into blood clots, reduces poisoning caused by acute pancreatitis when, due to inflammation of the pancreas, toxins begin to accumulate in the body.

During hypoxia, it reduces the activity of oxidative processes. By increasing coronary blood flow, it improves metabolism in the myocardium suffering from oxygen deficiency, directly in the area of ​​ischemia. It also affects the retina and optic nerve, making vision sharper.

Main active ingredient the drug increases the content of dopamine (a neurotransmitter that allows you to feel pleasure, not feel pain and is responsible for motor function muscles) in the brain.

Why is the drug prescribed?

Injectable Mexidol is prescribed when an illness combining mental and physiological reasons occurrence. Can also act as the only one remedy, and as part of complex therapy.

It is prescribed for:

  • traumatic brain injuries and their consequences;
  • acute myocardial infarction;
  • severe poisoning with antipsychotic drugs;
  • withdrawal syndrome;
  • withdrawal caused by drug addiction;
  • impaired blood circulation in the brain;
  • necrotizing pancreatitis;
  • peritonitis;
  • neurocirculatory dystonia (a set of disorders of the cardiovascular system);
  • dyscirculatory encephalopathy (affected by small arteries brain tissue);
  • primary open-angle glaucoma in different stages;
  • persistent anxiety in a state of neurosis.

In addition, Mexidol is also used for elderly patients who suffer from senile atherosclerosis.

Instructions for the use of Mexidol injections

The scope of use of Mexidol in injections is quite wide. The dosage, regimen and duration of use are determined by the doctor in each specific case. It takes into account not only the disease and its severity, but also the age of the patient (for those under 12 years of age, the drug is not approved), and the characteristics of the course of the disease. Therefore, it may deviate from the standard recommendations outlined in the manual.

Usually on initial stage(the first five days) treatment resorts to the most effective way- inject Mexidol intravenously. Why dilute it with water for injection and place a dropper set at 40 - 60 drops per minute. Or injected into a vein with a syringe, slowly, from 5 to 7 minutes. The daily dose is calculated based on the patient's body weight. For every kilogram of weight there should be 7 - 9 ml of succinate.

The Mexidol treatment regimen is determined by the disease. For example:

  • problems with cerebral circulation: 200-300 ml per day (the first two to four days) intravenously, then 100 ml of Mexidol intramuscularly - three times a day;
  • injuries of the skull and brain: two weeks, two to four times a day, droppers of 200 - 500 ml are given;
  • decompensation of dyscirculatory encephalopathy, when protective forces the body is not able to stop the pathology: intravenously (injections or droppers) 100 ml twice or thrice a day;
  • myocardial infarction: in the first five days, drip into a vein with a 5% glucose solution or 0.9% sodium chloride solution (every eight hours), from the ninth day you can inject it intramuscularly. The upper threshold for a single dose is 250, daily dose is 800 ml;
  • glaucoma: one - three intramuscular injection per day 100 - 300 ml.

How long therapy will last depends on what disease is being treated. So:

  • to normalize the blood supply to the brain, Mexidol is used for 10 to 14 days;
  • for atherosclerosis, injections will have to be given for 30 or even 40 days;
  • for encephalopathy, the course of treatment is shorter - usually two weeks is enough;
  • in case of necrotizing pancreatitis, the task of Mexidol is to reduce the severity of manifestations. The timing varies in each individual case;
  • It may take 7-10 days to eliminate intoxication with antipsychotics.

In any case, you should not stop treatment suddenly. In order not to cause discomfort, the dose should be reduced gradually.

Can it be used during pregnancy and lactation?

Research into how Mexidol can affect pregnancy, whether it crosses the placental barrier, and whether it can penetrate into breast milk, has not been conducted. Therefore, experts do not take the risk of calling the drug safe for this category of patients and do not allow women who are pregnant or breastfeeding to use it. During pregnancy, it is unknown how the medicine may affect the development of the fetus. When feeding breast milk The mother needs to temporarily switch the child to artificial formula.

Drug interactions

Quite often, Mexidol is one of the components healing process and is used in parallel with other medications. The dose and duration of use of Mexidol often depend on how they interact.

In combination with it, the human body is more strongly influenced by:

  • anticonvulsants;
  • antidepressants;
  • nootropics;
  • neuroleptics;
  • tranquilizers;
  • benzodiazepine derivatives;
  • painkillers.

In general, it can be noted that there were no negative results associated with the combination of Mexidol with any other medicine. But you should tell your doctor when you are taking any other medications at the same time.

Compatibility of the drug with alcohol

Mexidol, as mentioned above, reduces the effect of the toxic components of alcohol on the body. However, this does not mean that alcohol is not a hindrance for him. After all, even if the components of both are completely compatible, alcoholic drinks contraindicated for diseases for which Mexidol is prescribed. Neglecting the ban can end very badly.

There are situations when Mexidol cannot be used under any circumstances:

  • age under 12 years;
  • exacerbation of chronic renal failure;
  • liver failure;
  • individual intolerance to components.

Pregnancy and breastfeeding have already been discussed above.

Caution is needed when using this medication for those who suffer from increased or low blood pressure. And also for people driving cars and working with other complex equipment: there may be adverse reactions, which slow down the ability to quickly concentrate, distract attention and make you sleepy.

In general, Mexidol is a low-toxic drug, so the list of undesirable effects is small.

Rarely likely:

  • attacks of nausea;
  • state of constant drowsiness;
  • dry mouth;
  • constipation or, conversely, diarrhea;
  • flatulence;
  • swelling and rash on the skin;
  • blood pressure surges;
  • deterioration of sleep.

If the dose is incorrect or the period of therapy is extended without permission, when an overdose occurs, the above phenomena may become more active. Heartburn and vomiting are also possible.

Analogues of Mexidol injections

In pharmacies you can find quite a lot of analogues of Mexidol injections with a similar chemical composition.

Among them:

  • "Mexibel";
  • "Cerekard";
  • "Mexico";
  • "Neurox";
  • "Mexifin";
  • "Mexidant."

The doctor may prescribe other substitutes that are similar in their effects.

The drug "Mexidol" is very effective remedy for strokes, as well as disorders of brain function. It is successfully used both in surgery and psychiatry. This medicine is available in ampoules or tablets.

In the event that the tissues are insufficiently supplied with oxygen or its absorption is impaired, this remedy is very effective, since this drug differs in biological activity. Here's what the instructions for use say about the drug Mexidol: injections help develop the body's resistance to disorders cerebral circulation, and also to shock. In addition, thanks to its use in treatment, the patient’s memory improves and alcohol toxins are eliminated.

This drug is prescribed for problems in cerebral circulation, disorders of vascular tone and nervous system functions. In addition, the medicine "Mexidol" (injections) is successfully used for atherosclerotic disorders of brain activity and to relieve of this product You can relieve your craving for alcohol - a person simply loses the desire to drink.

The drug Mexidol is effective for many diseases. Injections are prescribed to patients intravenously or intramuscularly.

In order to prevent a sharp increase in adrenaline in the blood, this medicine is administered in a stream over five to seven minutes.

In case of cerebrovascular accident, the composition is administered dropwise at a rate of 6 drops per minute. The solution is water, which must be sterile. The doctor selects the dosage individually for each patient. The starting dose is usually one hundred milligrams three times a day. But gradually it increases. The duration of treatment and dosage of the drug depend on how severe the disease is. The maximum daily dose should not exceed eight hundred milligrams.

In case of stroke, the drug Mexidol is used. Intramuscular injections are given only at the onset of the disease, three to four days after its onset: first, intravenously, while maintaining a dose of 200-300 milligrams.

Those whose doctors have diagnosed “vegetative-vascular dystonia” or “dyscirculatory encephalopathy” should receive intramuscular injections of fifty or one hundred milligrams three times a day.

Patients with withdrawal syndrome are prescribed the drug Mexidol in the same way, with injections into the gluteal muscles of 100-200 milligrams three times a day. Sometimes intravenous drip injections are prescribed twice a day.

For treatment neurotic disorders do The dose ranges from fifty to four hundred milligrams per day.

Often people in old age develop a disease such as atherosclerotic dementia. In this case, the drug “Mexidol” is used, injections are given intramuscularly. The maximum dose of medication per day is three hundred milligrams.

In case of poisoning with antipsychotics, this medicine is prescribed intravenously in a stream of 50 milligrams per day (up to 300 mg).

In most cases, this drug is well tolerated, but dry mouth and nausea may occur occasionally.

There are also contraindications for the use of Mexidol. Injections (the instructions say) cannot be prescribed to those patients who have problems with the liver and kidneys. It is also not recommended to use this drug if you are allergic to vitamin B6. In addition, the main contraindications include pregnancy and lactation. This remedy is also not prescribed to children and adolescents.

In almost all patients for whom this drug was used, sleep normalized and anxiety. In addition, a person’s performance increases and irritability disappears. Many people say that the headaches have stopped, and the psychological stress has also begun to be felt less.

In this medical article you can read: medicine Mexidol. The instructions for use will explain in what cases the medicine can be taken, what it helps with, what are the indications for use, contraindications and side effects. The annotation presents the forms of release of the drug and its composition.

In the article, doctors and consumers can only leave real reviews about Mexidol, from which you can find out whether the medicine helped in the treatment of brain disorders, encephalopathy, ischemic attacks, traumatic brain injuries in children and adults. The instructions list analogues of Mexidol, prices of the drug in pharmacies, as well as its use during pregnancy.

Mexidol is an antioxidant drug used to improve cerebral metabolism and blood supply to the brain, to relieve withdrawal symptoms, as well as in acute purulent-inflammatory processes abdominal cavity.

Release form and composition

Mexidol tablets are sold in packs of 10 tablets and in plastic jars of 90 tablets. The solution for injection is available in clear or dark glass ampoules of 2 ml or 5 ml.

The composition of the drug in the form of an injection solution includes ethylmethylhydroxypyridine succinate as active substance(50 mg per 1 ml) and auxiliary components.

One tablet contains 125 mg of the active ingredient ethylmethylhydroxypyridine succinate, as well as a number of auxiliary components.

Also produce toothpaste Mexidol - Dent.

pharmachologic effect

Ethylmethylhydroxypyridine succinate is a membrane-protecting substance that reduces free radicals in organism. It has an antihypoxic (saturates the blood with oxygen), anti-stress, anticonvulsant effect. This medicine is a nootropic substance, improves memory, mental activity, stimulates learning, and neutralizes negative external influences on these processes.

Restores the sleep-wake cycle, reduces the rate of degenerative processes in the brain. Mexidol, instructions for use informs about this, protects lipids cell membranes from peroxidation, improves its viscosity, stimulates the work of enzymes that break down peroxide radicals, helps membranes stabilize their structure and maintain functionality.

Activates energy production in cell mitochondria. Accelerates the transmission of electrical impulses in synapses. Improves blood circulation and its rheological properties (viscosity and fluidity), reduces cholesterol levels. Has a pronounced therapeutic effect in the treatment of Parkinson's disease. The drug enhances the effect of tranquilizers, antipsychotics and antidepressants, as well as substances with sleeping pills and anticonvulsant effect. This allows you to reduce their doses and remove most side effects.

What does Mexidol help with in tablets and injections?

Indications for use are as follows:

  • conditions after acute intoxication with antipsychotic drugs;
  • autonomic dystonia syndrome;
  • asthenic conditions, as well as to prevent the development somatic diseases under influence extreme factors and loads;
  • anxiety disorders in neurotic and neurosis-like conditions; relief of withdrawal syndrome in alcoholism with a predominance of neurosis-like and vegetative-vascular disorders, post-withdrawal disorders;
  • consequences of acute cerebrovascular accidents, incl. after transient ischemic attacks, in the subcompensation phase as preventive courses;
  • mild cognitive disorders of atherosclerotic origin;
  • exposure to extreme (stress) factors;
  • mild traumatic brain injury, consequences of traumatic brain injury;
  • encephalopathy of various origins(dyscirculatory, dysmetabolic, post-traumatic, mixed).

Instructions for use

Mexidol tablets

Intended for oral administration. Therapeutic dose and the duration of use is determined by the doctor, based on the patient’s sensitivity to the drug. In most cases, treatment with the drug begins with an amount equal to 125-250 mg (1-2 tablets), gradually increasing the dose until the desired effect is obtained.

You should not take more than 6 tablets (800 mg) per day. Typically, the tablets are taken for 2-6 weeks. When relieving the withdrawal syndrome that accompanies alcoholism, it is recommended to take the drug for 5-7 days. The use of Mexidol should be discontinued gradually, reducing the amount of the drug over 2-3 days.

Solution

Can be administered intramuscularly or intravenously. The infusion method of administration involves diluting the drug in an isotonic NaCl solution. Jet injection The drug should be administered slowly - at least 5-7 minutes; for the drip method, the recommended rate of administration is 40-60 drops per minute.

The instructions for use of Mexidol explain that the daily dose should not be more than 1200 mg. Treatment of acute cerebrovascular accidents is carried out according to the following scheme: for the first 10-14 days, 2-4 times a day, 200-500 mg, administered intravenously; the next 14 days - 2-3 times a day, 200-250 mg, which should be administered intramuscularly. Reviews characterize this regimen for using the drug Mexidol as effective.

Treatment regimens for diseases

  • For withdrawal syndrome - IM, 100-200 mg 2-3 times a day or IV drip, 1-2 times a day for 5-7 days.
  • For neurotic and neurosis-like disorders - IM, 0.05-0.4 g per day.
  • For memory and intellect disorders - VM, 0.1-0.3 g per day for 14-30 days.
  • For discirculatory encephalopathy - IV stream or drip, 0.1 g 2-3 times a day for 14 days, and then IM, 0.1 g for 14 days.
  • For acute intoxication with antipsychotic drugs - IV, 0.05-0.3 g day for 7-14 days.
  • For course prophylaxis of dyscirculatory encephalopathy - IM, 0.1 g 2 times a day for 10-14 days.
  • In acute purulent-inflammatory processes of the abdominal cavity, it is prescribed on the first day both in the preoperative and postoperative periods.
  • At acute disorder cerebral circulation - IV drip, 0.2-0.3 g 1 time per day in the first 2-4 days, then IM, 0.1 g 3 times a day.
  • IRR – IM, 0.05-0.1 g 3 times a day.
  • For acute edematous (interstitial) pancreatitis - IV drip and intravenous injection, 0.1 g 3 times a day. Mild degree severity of pancreatic necrosis - IV drip and intramuscular injection, 100-200 mg 3 times a day. Average degree severity - IV drip, 0.2 g 3 times a day. Severe course - 0.4 g 2 times a day, then 0.3 g 2 times a day with a gradual decrease daily dose. Extremely severe course– 0.8 g day until persistent relief of the manifestations of pancreatogenic shock, when the condition stabilizes – IV drip, 0.3-0.4 g 2 times a day with a gradual decrease in the daily dose.

Doses depend on the form and severity of the disease, the prevalence of the process, and variations in its course. The drug is discontinued gradually, after a stable positive clinical and laboratory effect.

Side effect

According to the instructions, Mexidol can cause:

  • manifestations of dyspepsia;
  • allergies.

However, reviews from patients and doctors say that such reactions rarely occur.

Contraindications

  • hypersensitivity to the drug.
  • acute liver or kidney failure.

During pregnancy and breastfeeding

Pregnancy and lactation are contraindications to the use of Mexidol. This is due to the fact that strictly controlled studies of the effect of the drug on pregnant and lactating women have not been conducted.

For children

The use of the drug in pediatrics is indicated in the treatment of purulent neuroinfections, traumatic brain injuries, as well as for emergency care in cases of childhood traumatic brain injuries (100 mg once). Mexidol for children should be prescribed by a doctor who will monitor the child throughout its use. Local application V dental practice passes without complications.

special instructions

Pills

During the course of treatment with Mexidol tablets, you should follow special caution when driving vehicles and performing work involving danger to health and life. This is due to the fact that the drug has the ability to slow down the speed of psychomotor reactions and reduce concentration.

Injection

In patients with a predisposition to allergic reactions, hypersensitivity to sulfites, as well as in people with bronchial asthma, during treatment they may develop severe reactions hypersensitivity.

Drug interactions

At joint use Mexidol enhances the effect of benzodiazepine derivatives, antidepressants, anxiolytics, antiparkinsonian and anticonvulsants. The drug reduces toxic effect ethyl alcohol (alcohol).

Analogues of the drug Mexidol

Based on their structure, analogues containing an identical active substance are distinguished

  1. Mexiprim.
  2. Mexicofin.
  3. Metostabil.
  4. Medomexy.
  5. Mexidant.
  6. Mexican.
  7. Neurox.
  8. Cerecard.
  9. Ethylmethylhydroxypyridine succinate.

Price

In pharmacies, the price of Mexidol tablets (Moscow) is 265 rubles for 30 pieces of 125 mg each. Injections Mexidol ampoules 5% 2 ml 10 pcs. can be bought for 527 rubles, 5 ampoules of 5 ml cost 440 rubles.

Mexidol in injections is an antioxidant and neuroprotective drug. Available in ampoules of various volumes (2 and 5 ml), in packages with different numbers of ampoules. There are packages produced specifically for hospitals, which contain up to 100 ampoules. Active substance The drug,ate, was first invented in the 1980s at the State Research Institute of Pharmacology of the Russian Academy of Medical Sciences. Included in many modern delivery standards medical care on the territory of the Russian Federation.

Externally it is a colorless or yellowish odorless solution. In addition to ethat a concentration of 50 mg per 1 ml of solution, it contains water for injection and sodium metabisulfite.

Pharmacologically it has a multidisciplinary effect. Is good antioxidant, nootropic drug, membrane protector, neurotrophic drug due to increased tolerance to hypoxia. It has an unexpressed anticonvulsant, anxiolytic and tonic effect. Increases resistance to the effects of various stress factors (intoxication, stress, etc.).

There are properties of Mexidol that are not related to neurological practice: reducing intoxication during pancreatitis, improving blood circulation during myocardial ischemia, improving metabolic processes in eye tissues and helping to maintain integrity optic nerve and retina.

With intramuscular administration of the drug in the blood plasma, the concentration is determined in about 4-5 hours. Mexidol is excreted in the urine in the form of a conjugate with glucuronic acid.


Indications

Mexidol is indicated for many neurological diseases, as well as for certain symptoms:

  • Traumatic brain injuries.
  • Vestibulo-coordinating disorders.
  • Cognitive dysfunction.
  • Anxiety and neuroses.

The drug can also be used in the practice of other doctors for the following conditions:

  • Acute myocardial infarction.
  • Open angle glaucoma.
  • Alcohol intoxication.
  • Intoxication with narcotic and antipsychotic substances.
  • Purulent and inflammatory diseases abdominal cavity (including peritonitis), note – only as part of complex therapy!!!

Contraindications

There are a number of restrictions on the use of the drug:

  • Sharp or severe violations liver functions.
  • Acute kidney damage.
  • Allergic reactions to the drug (rare).
  • Pregnancy, lactation, childhood(no reliable studies have been conducted on the safety of using Mexidol).

Mode of application

Mexidol in the form of injections is administered intramuscularly or intravenously (stream, drip). At intravenous administration Mexidol is diluted in saline solution.

The drug is injected strictly slowly (5 minutes) in a stream; the injection rate reaches a maximum of 30-40 ml per minute. The maximum daily dosage should not exceed one gram (20 ml of concentrate).

The dosage is determined by the attending physician, as well as the duration of the course of treatment. These indicators depend on many factors: the type of pathology, the severity of the patient, the presence concomitant pathology etc.

For strokes, Mexidol is used for the first 2 weeks in doses of 200-400 mg 2 times a day, then they switch to intramuscular administration, and then to tablet forms.

In case of TBI, dyscirculatory processes, and withdrawal states, the schemes are similar. For vestibular lesions, dizziness of various origins, prevention of dyscirculatory encephalopathy, cognitive, anxiety disorders used intramuscular injection in doses of 100-300 mg 1-2 times a day, after which they switch to.

Dosages used for cardiac pathology purulent processes, glaucoma are not within the competence of the neurologist, the author of the site, and are given in full instructions on the use of Mexidol. Used medicine in these conditions only as part of complex therapy.

Side effects

A drug is proven and safe and generally has no side effects. The most common symptoms are nausea, dry mucous membranes, drowsiness, allergic reactions. Dizziness is not observed after using Mexidol; drowsiness may develop, which the patient perceives as dizziness. Or...

Overdose

The effects of overdose usually result in the development of drowsiness and quickly stop after stopping the use of the drug.

special instructions

When using Mexidol, a number of recommendations should be followed.

Sometimes, extremely rarely, in the presence of allergic reactions to sulfites, the presence bronchial asthma, with polyallergy, severe allergic reactions can develop. Such patients, when first prescribed Mexidol, require inpatient monitoring (ideally) or full outpatient monitoring.

There are a number of proven drug interactions Mexidol with other drugs. It should be remembered that the effect of antiparkinsonian drugs containing levodopa may be enhanced by anticonvulsants, benzodiazepine-based anxiolytics. More often it is positive effect, allowing you to reduce the dose, and, consequently, the risk of side effects from the use of these drugs. Mexidol also reduces the toxic effects of ethanol (including reducing intoxication and).

Storage conditions

Mexidol injections should be stored in a hard-to-reach place (protected from children), at room temperature. It is advisable to maintain optimal dry air and limit exposure to sunlight. The shelf life, subject to all storage conditions, is three years.

Analogs

Meskidol is original drug . Its generics, also containingate, are drugs such as Mexicor, Meksifin, Metostabil and lesser-known drugs.

Video commentary by the author

Price

Mexidol injections are available from pharmacies with a doctor's prescription. The price in pharmacies varies due to the markup of suppliers and the own markup of pharmacies, although Mexidol itself is included in the list of Vital and Essential Drugs. Current prices as of October 2017:

  • Ampoules 2 ml, No. 10 437-580 rubles.
  • Ampoules 2 ml, No. 50 1970-2285 rubles (used more often when purchasing to hospitals and hospitals).
  • Ampoules 5 ml, No. 5 415-555 rubles.
  • Ampoules 5 ml, No. 20 1640-1810 rubles (used more often for purchases in hospitals).

In comparison with the author’s archive (ampoules 2 ml, No. 10 price 365-527 rubles, ampoules 2 ml, No. 50 2000-2400 rubles, ampoules 5 ml, No. 5 cost 360-495 rubles, ampoules 5 ml, No. 20 1600-1820 rubles), prices increased significantly (up to 20%) for small-sized packages and decreased very slightly for large packages, which generally reflects negative price dynamics for the average person.

You should not self-medicate, it can be dangerous! Before using Mexidol, consult your doctor!