Midantan: instructions for use of tablets. Medicinal reference book geotar
Each tablet contains: active ingredient - amantadine hydrochloride – 100 mg; excipients: lactose monohydrate, starch 1500, partially pregelatinized corn starch, croscarmellose sodium, talc, stearic acid, potato starch, opadry II (contains: polyvinyl alcohol, partially hydrolyzed, macrogol 3350, talc, titanium dioxide (E 171), aluminum varnish based on yellow quinoline (E 104), yellow iron oxide (E 172)).
Indications for use
Parkinson's disease, parkinsonism syndrome (rigidity, tremor, hypokinesia).
Neuralgia in herpes zoster caused by the Varicella zoster virus.
Prevention (including in combination with vaccination) and treatment of influenza A.
Contraindications
Liver failure, chronic renal failure, psychoses (including history), thyrotoxicosis, epilepsy, angle-closure glaucoma, hyperplasia prostate gland, arterial hypotension, chronic heart failure stage II-III, state of excitation, predelirium, delirious psychosis, women planning pregnancy, pregnancy, lactation period, gastric ulcer, simultaneous administration triamterene and hydrochlorothiazide, increased sensitivity to amantadine.
Directions for use and doses
In adults daily dose amantadine is 200 mg. Prescribe 100 mg 2 times a day. In persons aged 65 years and older, the daily dose of amantadine should be reduced to 100 mg per day.
Use in pediatrics: for children aged 6-9 years, the daily dose is from 2 to 4 mg/kg/day, but not more than 150 mg per day; at the age of 9-12 years, the daily dose is 200 mg (100 mg 2 times a day).
Prevention of influenza should be carried out before the onset of an influenza epidemic and before or after contact with persons suffering from acute illness. respiratory disease. Duration of use is at least 10 days after contact.
If amantadine is used as chemoprophylaxis in combination with an inactivated influenza virus vaccine, the drug should be used for 2-4 weeks after vaccination. If the use of the vaccine is contraindicated, then amantadine must be used for prophylaxis throughout the entire duration of the influenza epidemic.
Treatment for influenza should begin as early as possible, preferably within 24 to 48 hours after the onset of symptoms, and should be continued for 24 to 48 hours after symptoms have resolved.
For herpes zoster, the drug should be used at a dose of 100 mg 2 times a day for 14 days. Treatment should begin as soon as possible after diagnosis. If post-herpetic pain does not go away, treatment can be continued for the next 14 days.
For the treatment of parkinsonism in adults, the dose of amantadine is 100 mg 2 times a day, if monotherapy is used. The onset of action of amantadine usually occurs within 48 hours. The starting dose of amantadine is 100 mg per day for patients receiving high doses of other antiparkinsonian drugs. After taking amantadine at a dose of 100 mg once daily for 1 to several weeks, the dose can be increased if necessary to 100 mg twice daily. Sometimes in patients with insufficient response to therapy, the dose of amantadine can be increased to 400 mg per day in several doses.
Often after a few months of use medicine there may be a decrease in its effectiveness. Temporary discontinuation of amantadine for 3-4 weeks and then resumption of use may result in restoration of the therapeutic effect in some patients. In this case, it is necessary to make a timely decision on the prescription of other antiparkinsonian drugs.
When amantadine and levodopa are prescribed simultaneously, rapid therapeutic effect. The dose of amantadine should be constant - 100 mg per day or 100 mg 2 times a day, while the daily dose of levodopa is gradually increased. For patients who require a reduction in the dose of levodopa due to the development of side effects, it is possible to increase the dose of amantadine.
When treating drug-induced extrapyramidal reactions in adults, the usual dose of amantadine is 100 mg 2 times a day. Sometimes in patients, the dose may be increased to 200 mg per day or up to 300 mg per day in divided doses.
In case of impaired renal function, depending on creatinine clearance, the following dose adjustments are recommended:
Side effect
From the outside immune system: allergic reactions, including anaphylactic reactions, fever;
From the side of the central nervous system: mental agitation, irritability, paranoid and manic reactions, depression, motor agitation, involuntary muscle contraction, tremors, convulsions, gait disturbances, paresthesia, changes in the EEG, headache, dizziness, sleep disorders, ataxia, slurred speech, decreased libido, fatigue, weakness, hyperkinesia; decreased visual acuity, pinpoint subepithelial or other corneal opacities, corneal edema, paralysis optic nerve, keratitis, visual hallucinations, increased sensitivity to light;
From the outside digestive system: diarrhea, dysphagia, anorexia, nausea, constipation, dry mouth;
From the outside respiratory system: shortness of breath, dry nasal mucosa, tachypnea, pulmonary edema, acute respiratory failure;
From the outside of cardio-vascular system: syndrome marble leather(livedo) with swelling of the ankles and legs; development or worsening of heart failure, orthostatic hypotension; prolongation of the QT interval, arrhythmias, including malignant arrhythmias, tachycardia, ventricular fibrillation, cardiac arrest;
Blood disorders: rarely leukopenia, neutropenia, leukocytosis, agranulocytosis, thrombocytopenia;
From the urinary system: in patients with prostatic hyperplasia - difficulty urinating; polyuria, nocturia;
Dermatological reactions: eczema, itching, increased sweating, skin rash, the appearance of a bluish coloration of the skin of the upper and lower limbs(livedo reticularis);
From laboratory parameters: increased activity of CPK, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, and the content of bilirubin, urea nitrogen, creatinine in the blood serum.
Overdose
An overdose of amantadine can be fatal.
Symptoms:
Central nervous system: hyperreflexia, motor restlessness, seizures, extrapyramidal signs, torsion spasms and other disorders neuromuscular transmission, dilated pupils, dysphagia, confusion, disorientation, delirium, visual hallucinations, myoclonus.
Respiratory system: hyperventilation, pulmonary edema, respiratory failure, including respiratory distress syndrome adults.
The cardiovascular system: sinus tachycardia, arrhythmia, hypertension. Gastrointestinal tract: nausea, vomiting, dry mouth.
Urinary system: urinary retention, impaired renal function, including increased urea and decreased creatinine clearance.
Amantadine overdose with combination treatment: The effects of anticholinergic drugs are increased with concomitant use of amantadine. Acute psychotic reactions (which may be identical to atropine poisoning) may occur with use large doses anticholinergic drugs. If alcohol or central nervous system stimulants were ingested at the same time, then signs and symptoms acute poisoning amantadine may worsen or change.
Treatment: There is no specific antidote. Measures: induction of vomiting and/or gastric lavage, it is advisable to use Activated carbon or laxative. Since amantadine is excreted mainly unchanged in the urine, renal function should be maintained (forced diuresis if necessary). Acidification of urine promotes its excretion. Hemodialysis is not effective enough for amantadine poisoning.
Interaction with other drugs
With simultaneous use, the side effects of antiparkinsonian drugs may increase.
When used simultaneously with thiazide diuretics, the possibility of the development of toxic effects of amantadine (ataxia, agitation, hallucinations), probably due to a decrease in its renal clearance, cannot be excluded.
Acute confusion in an elderly patient is possible when used concomitantly with co-trimoxazole.
When used simultaneously with quinine or quinidine, it is possible to reduce the excretion of amantadine in the urine.
Features of application
Prescribe with caution to patients with impaired renal function, when used simultaneously with other antiparkinsonian drugs, as well as to persons over 65 years of age. In such cases, adjustment of the amantadine dosage regimen is required. In patients with hyperreflexia, treatment should be withdrawn gradually.
Information about the effectiveness of amantadine in reducing extrapyramidal disorders during treatment with antipsychotic drugs (drug-induced parkinsonism) is contradictory.
During treatment, alcohol consumption is contraindicated.
During the treatment period, you should not engage in activities that require increased concentration attention and rapid psychomotor reactions.
In patients with parkinsonism, treatment should not be stopped abruptly. This may cause deterioration clinical symptoms. The dose should be reduced gradually.
Midantan is an antiparkinsonian drug that is quite effective in multiple sclerosis. This remedy is not a panacea. It is prescribed in order to reduce negative symptoms in this type of disease. Therapy in these cases is lifelong.
The drug has wide range actions. It is prescribed for influenza type, and for Parkinson's disease, for various kinds neuralgia, with multiple sclerosis.
Side effects and contraindications
In case of drug overdose The following side effects may occur:
- urinary retention (incontinence) (especially if the patient has a history of diseases associated with the kidneys or bladder);
- headache;
- dizziness;
- nervous overexcitation;
- insomnia;
- unnecessary muscle motor skills;
- convulsions;
- heart rhythm disturbance;
- Gastrointestinal disorder: nausea, vomiting, stool disorder, dry mouth;
- dermatosis
Contraindications for taking this drug are the following diagnoses in the anamnesis:
- epilepsy;
- renal failure;
- prostate pathology;
- arterial hypotension.
Midantan is not prescribed during pregnancy and lactation.
Carefully this drug prescribed to persons who are predisposed to allergic dermatitis, persons suffering from alcoholism, elderly persons, persons with various types of mental disorders and pathology.
The patient must be closely monitored during therapy. If they appear adverse reactions, then it is necessary to either adjust the therapy or abandon further use of the drug.
Main active ingredients and pharmacodynamic mechanism
One tablet of the drug contains:
- 100 mg amantadine sulfate (main active substance, which has anti-inflammatory and antiparkinsonian effects);
- auxiliary components (magnesium stearate, titanium dioxide, silicon dioxide).
The drug has positive influence on neural processes, reduces potential opportunity their destructive work.
For influenza groups, and the main active Midantan substance has an inhibitory effect on viral cells.
Release form of the drug
The drug is available in two forms:
- in tablet form (yellow-orange tablets, tasteless and odorless, double-convex, available in packs of 30 pieces - 3 blisters of 10 pieces each);
- in the form of a solution.
Photo classic shape The release (tablet form) of this product can be viewed below.
The drug is dispensed at the pharmacy strictly according to a doctor's prescription. It can be stored in a dry, dark place, at a temperature that does not exceed +25 degrees. Best before date, according to the manufacturer's instructions, does not exceed 5 years.
Midantan must be hidden from children or stored in a place as inaccessible to them as possible.
Judging by the instructions for use, Midantan is taken orally, after meals or intravenously (according to the regimen prescribed by the doctor). Daily dosage at various diseases different. The basic principle of use is to increase the dose gradually (usually start with 100 mg of the drug, gradually increasing the volume of consumption).
Accepted by the hour. Break (maximum possible) - 6 hours. The last appointment is strictly after dinner. Maximum possible dose- 600 mg. per day for adults and 150 mg. per day for children. Elderly people are prescribed gentle therapy in any case. Therapy does not last more than 14-17 days, if we are talking specifically about children and specifically about the prevention and treatment of group A influenza.
If Midantan is prescribed in the form of a solution and administered intravenously, then the daily dose according to the instructions also does not exceed 600 mg. The dosage can be reduced only if pathology is identified renal system. This type of therapy is carried out over 7 - 14 days..
Classic dosage regimen for Parkinson's disease
- Days 1−3 - 100 mg. per day;
- Days 4−7 - 200 mg. per day;
- 8 - 14 (17) days - 300 mg. per day;
- 18 - 30 days (or longer) - 300 mg. per day.
Exist special instructions and instructions pharmacists regarding the prescription and use of this drug.
Latin name: Midantan
ATX code: N04BB01
Active substance: amantadine
Manufacturer: Borisov plant
medicines, Republic of Belarus.
Release from the pharmacy: on prescription
Storage conditions:+25 degrees
Best before date: 5 years.
International generic name drug – INN – Amantadine. The drug "Midantan" refers to drugs used in the treatment of Parkinson's disease. In addition, the drug is used in the treatment of influenza type A. The active substance of the drug blocks the penetration of the pathogen into cells.
Indications for use
The medicine has a small list of indications. Midantan tablets are prescribed in the following cases:
- Parkinson's disease
- Muscle stiffness
- Tremor
- Hypokinesis
- Neuralgia caused by Varicella zoster virus
- Treatment of influenza type A
- Prevention in combination with vaccination against influenza virus serotype A.
Composition and release forms
The active substance of the antiparkinsonian drug is amantadine. The remaining components are auxiliary substances and shell elements.
Midaltan tablets contain 100 mg active substance. Orange color. There is a dividing chamfer on one side. The tablets are packed in blisters of 10 pcs. There are 10, 20, 50 and 100 pieces in a box.
Medicinal properties
Amantadine stimulates the production of dopamine in neuronal depots and increases the sensitivity of receptors to the mediator. Midaltan blocks the flow of calcium ions into neurons, which reduces the rate of destruction nerve cells. At the same time, the manifestations of rigidity and stiffness of muscle tissue are reduced.
Amantadine is absorbed in the stomach. Maximum concentration active component observed in the blood after 5 hours. The half-life ranges from 15 to 30 hours. Amantadine penetrates the membranes of the brain, the placental barrier, and is excreted in breast milk.
The active substance is excreted unchanged through the urinary system.
Midantan. Instructions for use
Average price – 150 rubles
The drug is taken orally after meals. The last dose is after dinner. For Parkinson's disease, 1/3 tablet is prescribed every 6 hours for 3 days. Then, on days 4–7 of therapy, the dose is increased to 200 mg per day.
Next 14 days take 1 tablet 3 times a day. From the 21st day of therapy, the drug is taken at a dosage of 300–400 mg per day. The maximum amount is 6 tablets per day. Duration of treatment is from 2 to 4 months.
In case of impaired renal function, the dose is adjusted depending on the speed glomerular filtration and increase the interval between drug doses.
- Filtration rate 60–80 ml/min – 1 tablet every 12 hours
- 50–60 ml/min. – 1 day 2 pcs. every 12 hours, the next - 0.5 pcs. 2 times a day
- 20–30 ml/min. - 2 pcs. 2 times per week
- 10–20 ml/min. – 1 tablet 3 times a week
- less than 10 ml/min. – 2 tablets 1 time per week and 1 pc. 1 time every 2 weeks.
For elderly patients, reduced dosages of the drug are used. The doctor selects the treatment regimen.
Abrupt withdrawal of the drug should not be allowed. This may increase the symptoms of Parkinson's disease.
Contraindications and precautions
The drug has an extensive list of contraindications. The use of Midantan is prohibited in the following cases:
- Liver and kidney failure
- History of psychosis
- Hyperthyroidism
- Epilepsy
- Glaucoma
- Prostate adenoma
- Against the background of low blood pressure
- Heart failure
- Alcohol delirium
- Binge drinking
- Treatment with triamterene and hydrochlorothiazide
- Gestation period and lactation
- Individual intolerance.
During the treatment of Parkinson's disease with the drug Midantan, the consumption of alcoholic beverages is prohibited. It is not advisable to drive a car or perform work that requires increased attention and precision of movements.
Use during pregnancy
The drug is prohibited for use in the first 12 weeks of pregnancy. In the 2nd and 3rd trimester of pregnancy and lactation, treatment with Midantan is carried out under the supervision of a doctor.
Cross-drug interactions
When taking ethanol and drugs to stimulate the central nervous system at the same time, the side effects of Midantan may increase.
The active substance of the drug enhances the effect of levodopa and psychostimulants. Minantan can be used simultaneously with other antiparkinsonian drugs.
Side effects
Side effects of the drug mainly affect nervous system. These are agitation, convulsions, sleep disturbances, vertigo, hallucinations.
In addition, patients presented the following complaints:
- Tachycardia
- Reduced pressure
- Development of arrhythmia
- Dry mouth
- Nausea
- Urinary retention due to prostate hyperplasia
- Dermatoses
- The appearance of a blue color on the skin of the extremities.
When unpleasant symptoms You should discuss with your doctor a replacement drug or adjust the dose of Midantan.
Description of overdose
- Nervous system – excessive excitement, convulsions and spasms, development of extrapyramidal disorders, disorientation, hallucinations.
- From the urinary system - anuria, urinary retention, increased urea content in the urine.
- Respiratory organs – pulmonary edema, respiratory failure.
- Heart – tachycardia, rhythm disturbance.
- Gastrointestinal tract - nausea, vomiting.
In case of overdose, gastric lavage and forced diuresis are indicated. Hemodialysis is ineffective.
Analogues of the drug
There are few complete analogues of Midantan. There are many medications that have a similar effect, but replacement should be discussed with your doctor.
Substitutes for this drug:
Manufactured by the Merz concern, Germany.
Price packaging in 2 bottles of 200 ml in the Russian Federation is 1,500 rubles.
Pros:
- Complete analogue
- Variety of dosage forms
- Expected Result.
Minuses:
- Price
- For the solution – hospital treatment is required
- The spectrum of side effects is similar to Midantan.
A drug that has a similar effect.
Produced in Ukraine. The cost of the medicine is 22 UAH. per package No. 50 for residents of Ukraine.
In Russia the price packages range from 22 to 100 rubles.
Pros:
- Similar action
- Larger list of indications for use
- Can be used for children over 5 years of age in the treatment of extrapyramidal disorders.
Minuses:
- More contraindications and side effects
- Prohibited for simultaneous use with an extensive list of medications
- Not used for the treatment or prevention of influenza.
For one tablet:
active substance: amantadine hydrochloride - 100,000 mg;
Excipients: lactose monohydrate - 105,000 mg, partially pregelatinized corn starch (starch 1500) - 10,575 mg, croscarmellose sodium - 15,000 mg, talc - 7,270 mg, stearic acid - 2,480 mg, potato starch - up to an average tablet core weight of 250,000 mg, opadry II series 85F 32554 (yellow) - 12,000 mg. Composition of opadry II series 85F 32554 (yellow): polyvinyl alcohol, partially hydrolyzed - 40.000%, macro-gol 3350 - 20.200%, talc - 14.800 Finishing pigment (titanium dioxide E 171 -22.320%, aluminum varnish based on yellow quinoline E 104 - 2.430%, iron oxide yellow E 172 - 0.250%) - 25.000%.
Description:Round biconvex tablets, coated film-coated, yellow color. The cross section shows two layers.
Pharmacotherapeutic group:Antiparkinsonian drug ATX:N.04.B.B.01 Amantadine
Pharmacodynamics:Antiparkinsonian drug, tricyclic symmetric adamantamine. Blocks glutamate
NMDA -receptors (including in the substantia nigra), thereby reducing the excessive stimulating effect of cortical glutamate neurons on the neostriatum, which develops against the background of insufficient dopamine release. By reducing the flow of ionized Ca2+ into neurons, it reduces the possibility of their destruction. IN to a greater extent affects stiffness (rigidity and bradykinesia). Pharmacokinetics:After oral administration, it is well absorbed from the gastrointestinal tract. Maximum plasma concentration after 5 hours; The half-life of amantadine sulfate is 12-13 hours. Amantadine hydrochloride is 30 hours. It is excreted unchanged by the kidneys.
Indications:Parkinson's disease, parkinsonism syndrome.
Contraindications:Hypersensitivity, liver failure, chronic renal failure, psychosis (history), thyrotoxicosis, epilepsy, closed-angle glaucoma, prostatic hyperplasia, arterial hypotension, heart failure
II - III Art. agitation, predelirium, delirious psychosis, pregnancy (first trimester), lactation, simultaneous use of triamterene and hydrochlorothiazide. Carefully:Orthostatic arterial hypotension, allergic dermatitis, pregnancy (
II - III trimester), elderly age, alcoholism, mental disorders (including a history). Directions for use and dosage:Inside, after eating. For Parkinson's disease, the initial dose is 100 mg/day with an interval of 6 hours (last dose before dinner) for 3 days; from 4 to 7 days - 200 mg/day; for 2 weeks - 300 mg/day: from the 3rd week, depending on the patient’s condition, 300-400 mg/day. The maximum dose is 600 mg/day.
P In case of impaired renal function, the dose is reduced and the intervals between doses are increased at a glomerular filtration rate of 80-60 ml/min - 100 mg every 12 hours, 60-50 ml/min - dosages of 200 mg and 100 mg alternate every other day. 30-20 ml/min - 200 mg 2 times a week. 20-10 ml/min - 100 mg 3 times a week, less than 10 ml/min - 200 mg once a week and 100 mg every second week. In elderly patients, reduced doses are used.
Side effects:From the nervous system: motor or mental agitation, convulsions, headache, dizziness, irritability, insomnia, tremor, mental disorders accompanied by visual hallucinations.
From the cardiovascular system: heart failure, tachycardia, orthostatic hypotension, arrhythmogenic effect.
From the authorities gastrointestinal tract : dry mouth, nausea, anorexia, dyspepsia.
From the urinary system: acute delay urine in patients with prostatic hyperplasia, polyuria. nocturia.
Others: dermatosis, the appearance of a bluish coloration of the skin of the upper and lower extremities, decreased visual acuity.
Interaction: Medicines that stimulate the central nervous system and increase the risk of side effects. Enhances the effect of levodopa. psychostimulants. Compatible with central anticholinergics and other antiparkinsonian drugs. Special instructions:Information about the effectiveness in the treatment of extrapyramidal disorders during treatment with antipsychotic drugs (drug-induced parkinsonism) is contradictory. Therapy should not be stopped suddenly, because a sharp exacerbation of the disease is possible.
The use of ethanol while taking the drug is contraindicated.
Impact on the ability to drive vehicles. Wed and fur.:During the treatment period, it is necessary to refrain from driving vehicles and potentially engaging in activities dangerous species activities that require increased concentration and speed of psychomotor reactions. Release form/dosage:Film-coated tablets, 100 mg.
Package: 10 tablets per blister pack made of polyvinyl chloride film or unplasticized PVC film and flexible packaging based on aluminum foil or aluminum foil or a combined material based on foil. 100 tablets in glass jars with a screw neck, sealed with screw caps, or in polymer jars, sealed with polymer screw caps, or in polymer jars, sealed with polymer clamp caps. Each jar or 2, 5 or 10 blister packs along with instructions for medical use placed in a cardboard pack. Storage conditions:List B. In a dry place, at a temperature not exceeding 25°C. Keep out of the reach of children.The main topic of the article is the drug "Midantan". Instructions for use, popular analogues and reviews of the drug will be discussed in detail below.
Release form of the drug and its price
How much does Midantan cost? The price of the medicine is low, which makes it affordable for most patients. The minimum cost is 127 rubles, and the maximum price does not exceed 150 rubles. This, by the way, is considered one of the main advantages of the drug.
Most often, pharmacies offer tablets. "Midantan" is also available in the form of a solution for infusion. How to take the drug correctly will be discussed in the article.
Indications for use
In what cases is Midantan prescribed? Instructions for use indicate that use is advisable for the following pathologies:
- Parkinson's disease.
- Parkinsonism syndrome.
As you can see, the drug helps fight quite serious illnesses. One of them is parkinsonism syndrome. This disease most often diagnosed in older people. Just imagine, according to statistics, this syndrome Every fifth elderly person on the planet has it in one form or another.
How does Midantan work?
How does Midantan work? The mechanism of action of the drug is due to the presence of the active substance amantadine. The antiviral and antiparkinsonian effect is what the main component provides. It is thanks to him that the drug fights Parkinson's disease. In addition, amantadine blocks NMDA receptors. Due to this, the supply of Ca2+ decreases, which reduces the likelihood of destruction of neurons in the central nervous system.
Method of taking the drug
Now is the time to talk about how to take Midantan. The instructions for use perfectly describe the method of taking the tablets.
The drug should be taken only after meals. The course of treatment with these tablets includes several stages. Let's take a closer look at them.
- First stage. The patient takes 100 mg of the active substance per day. It is important to remember the interval between doses of the drug. The medicine must be taken every 6 hours, but not earlier.
- Stage two. This stage begins on the 4th day of therapy and lasts 3 days. As for the dose, it is doubled, i.e. you need to take 200 mg per day at the same intervals.
- Third stage. Its duration is two weeks. The dose of the drug is 300 mg per day.
In some cases, the dose can reach 400 mg per day, but only a doctor can make this decision. The maximum daily amount of amantadine is 600 mg. If the patient has kidney problems, the dose is reduced and the interval between doses increases.
How does the medicine interact with other drugs?
There are cases when Midantan needs to be taken along with other drugs. Instructions for use advise caution when using tablets in combination with the following drugs:
- Medicines that stimulate the human nervous system. Taking the drug with such drugs can cause serious complications throughout the nervous system.
- Psychostimulants. If the drug "Midantan" is taken with one of these drugs, the doctor carefully reviews the dose of both one and the other drug.
So, the drug can be taken with other drugs, but with caution. The occurrence of any change or deterioration in well-being should be a signal to stop taking this drug and contact your doctor.
Side effects while taking the drug
What side effects Can the drug "Midantan" help? Instructions for use contain a large list possible complications, if they occur, you must stop taking them. So, the side effects are as follows:
- Headache.
- Nausea.
- Anorexia.
- Dermatosis.
- Decreased visual acuity.
- Tremor.
- Heart failure.
- Dermatosis.
This is not the entire list of possible complications that may well arise when using the drug. Therefore, it is necessary to take Midantan with extreme caution, carefully monitoring the well-being and condition of the body.
The drug "Midantan": reviews of therapy
This is the one rare case, When negative reviews there is simply no information about the drug. Many patients have noted the effectiveness of this drug. The low price is also considered another big plus. An improvement in the patient’s condition, albeit small, occurs already on the third day after the very first appointment.
The drug also received a good rating from doctors. They claim that the drug is absolutely safe and effective. That is why it is prescribed to almost all patients suffering from parkinsonism syndrome. It is worth understanding that this remedy It cannot completely cure the disease, but it can slow down its development and make the patient’s life more comfortable.
"Midantan": analogues of the drug
Now it's time to talk about analogues of the drug "Midantan". There are quite a lot of analogues. The most popular of them:
- "Gludantan".
- "PC-Merz".
- "Viregit-K".
What's the difference between them and are they good at their jobs? Let's consider this question.
The drug "Gludantan"
The first analogue with which I would like to introduce the reader is “Gludantan”. As in the case of the drug "Midantan", its active ingredient is amantadine. This medicine It is also available in two popular forms - tablets and solutions for infusion.
The drug "Gludantan" is prescribed for the following diseases:
- Parkinson's disease.
- Gripp A.
- Parkinsonism syndrome, etc.
"Gludantan" is taken in the same way as "Midantan". The course of treatment consists of three stages. Another important point- You should not drink alcohol during treatment, even in the smallest doses.
The next point is contraindications. The drug has quite a lot of them. That is why before starting to take the medicine, the patient undergoes a serious examination. So, the contraindications are as follows:
- First trimester of pregnancy.
- Alcoholism.
- Angle-closure glaucoma.
- Mental disorders.
This is not the entire list of contraindications. More details about them can be found in the instructions for use. The drug has side effects. Let's list them:
- Motor excitement.
- Mental disorders.
- Dermatosis.
- Nocturia.
- Dry mouth.
- Nausea.
If these disorders occur, you should immediately stop taking the drug and consult a doctor.
The drug "PK-Merz"
Another medicine that is considered an analogue of the drug "Midantan" is "PK-Merz". And here the active ingredient is amantadine. As for the application, it is exactly the same.
We need to talk in more detail about side effects drug. They are as follows for the drug:
- Headache.
- Tachycardia.
- Polyuria.
- Nocturia.
- Nausea.
- Dry mouth.
- Arrhythmogenic effect.
Now let's look at cases where the use of this medicine is strictly prohibited:
- Elderly age.
- Alcoholism.
- Second and third trimester of pregnancy.
- Epilepsy.
- Allergic dermatitis.
This is not the entire list of contraindications for the drug "PK-Merz". In any case, the attending physician, based on the examination results, will be able to select an effective but safe dose.