Monural or fosfomycin which is better. Monural - an antibiotic for the treatment of cystitis

Monural (MONURAL, non-proprietary international name Fosfomycin) is a broad-spectrum antibiotic.

The drug belongs to the group of uroantiseptics, the main purpose of which is the treatment and prevention of inflammatory bacterial diseases of the urinary tract. The drug has a good bactericidal effect, which is applicable against most gram-positive (enterococcus, staphylococcus) and gram-negative (cytobacteria, enterovirus, Klebsiella, Morganella, Proteus, Pseudomonas) pathogens.

A distinct advantage of Monural from other drugs is its one-time use for acute cystitis. Only 1 sachet is enough for a course of treatment. This dosing regimen eliminates the need for patients to take other antibiotics for several days.

Clinical and pharmacological group

Antibiotic of the group of phosphonic acid derivatives. Uroantiseptic.

Conditions for dispensing from pharmacies

Dispensed with a doctor's prescription.

Prices

How much does Monural cost? The average price in pharmacies is 470 rubles.

Release form and composition

Monural is produced in the form of granules, from which a solution for oral use is prepared: white, with a tangerine scent (in multi-layer laminated bags, 1 packet in a cardboard pack).

• Active ingredient - fosfomycin trometamol: in 1 package - 3.754 g (including fosfomycin - 2 g) or 5.631 g (including fosfomycin - 3 g).

Auxiliary components: sucrose, saccharin, orange and tangerine flavors.

Pharmacological effect

Monural is a broad-spectrum antibiotic.

The drug has a bactericidal effect, inhibits the first stage of bacterial cell wall synthesis. Monural is a structural analogue of phosphoenol pyruvate. May enter into a competitive interaction with the enzyme N-acetyl-glucosamino-3-o-enolpyruvil transferase. The result is specific, selective and irreversible inhibition of this enzyme, which ensures the absence of cross-resistance with other classes of antibiotics and the possibility of synergy with other antibiotics.

The drug is active against most gram-positive and gram-negative microorganisms.

Indications for use

What does it help with? Monural is used for the following types of cystitis:

1. with a slight excretion of bacteria in the urine (bacteriuria);
2. Chronic post-traumatic cystitis with bacteriuria;
3. Cystitis during pregnancy;
4. Postoperative cystitis.

Prescribe Monural for cystitis, 3 g (1 sachet) per day for 1-2 days (depending on the severity of the process).

Contraindications

The drug is not prescribed:

• in case of allergic reactions to fosfomycin or other components;
• patients with severe renal failure;
• children under five years old.

Use during pregnancy and lactation

During pregnancy, Monural is prescribed only according to strict indications (subject to massive bacteriuria and the absence of effect from other therapy).

In cases where the drug is taken during lactation, breastfeeding should be avoided.

Dosage and method of administration

The instructions for use indicate that Monural is prescribed for adults 3 g 1 time/day. The course of treatment is 1 day. If necessary (for severe or recurrent infections, for elderly people), the drug can be repeated at a dose of 3 g after 24 hours.

In order to prevent urinary tract infections during surgery and transurethral diagnostic procedures, the drug is taken in a dose of 3 g 3 hours before surgery and 3 g 24 hours after the first dose.

Children over 5 years old the drug is prescribed in a dose of 2 g only once.

When prescribing the drug patients with renal failure the dose should be reduced and the interval between doses increased.

Before taking, the granules are dissolved in 1/3 glass of water. The drug is taken 1 time/day on an empty stomach 2 hours before or after meals (preferably before bedtime), after emptying the bladder.

Side effects

Side effects of the drug can manifest themselves in the form of the following body reactions:

1. Allergic reactions in the form of skin rash and itching.
2. From the gastrointestinal tract - nausea, vomiting, heartburn, diarrhea. With plenty of drinking, these phenomena usually disappear.

Overdose

The risk of developing an overdose of Monural is minimal.

Therapy: forced diuresis.

special instructions

When prescribing Monural to patients with diabetes mellitus, it should be taken into account that 1 package containing 2 g of fosfomycin contains 2.1 g of sucrose, and 1 package containing 3 g of fosfomycin contains 2.213 g of sucrose.

Before you start taking Monural, you should tell your doctor if:

• you are allergic to any components of the medication;
• you have ever had asthma or liver disease;
• if you are pregnant, breastfeeding or think you may be pregnant;
• you are taking any medications, especially cisapride (Propulsid) and metoclopramide (Cerucal), as well as over-the-counter medications, herbs, dietary supplements, and vitamins.

It should also be borne in mind that monural can increase diarrhea, although usually the patient's diarrhea is not an obstacle to prescribing this drug.

Drug interactions

When used simultaneously with metoclopramide, a decrease in the concentration of fosfomycin in the blood serum and urine is possible (this combination is not recommended).

In the treatment of cystitis, the medicine Monural is used.

The drug is produced abroad (Switzerland), its price is quite high.

The basis of Monural is .

Similar drugs act no less effectively on the disease, while the cost for most patients is lower than the original medicine.

Before changing the medication, you need to consult a doctor.

basic information

Nolitsin

The medicine is produced by Slovenian pharmacists. At a low price, nolitsin effectively copes with cystitis. Release form: tablets. prescribed for the treatment of pelvic infections. The drug has a number of contraindications:

Effective in the treatment of urethritis, cystitis, and intestinal infections. It acts quickly, the disease recedes. The active substance of nolicine is.

Prices in Russia and Ukraine

Analogues of Monural vary in price and degree of purification of the original active substance.

Prices for Russian analogues were given above.

Substitute drugs produced in Ukraine are represented by the following names:

1. Dioxidin. Release form powder. Treatment of purulent infections. Cost from 200 UAH. (440 rub.) for 10 ampoules.
2. Dixizol. Bactericidal drug. Solution form of use. Cost 50 ml – 50 UAH. (110 rub.).
3. Uroxoline. Pills. Contraindicated for kidney and liver dysfunction. The cost of packaging is 50 tablets. – 14.50 UAH. (32 rubles).
4. Urofoscin. Antibacterial drug. Not for children under 12 years of age, patients with kidney or liver problems. Cost – 120 UAH. (260 rub.).
5. Cistarol. Granules. Urogenital infections in the acute stage. Price – 150 UAH. (330 rub.)

Analogs are presented quite extensively; to choose a medicine, you need to consult with doctors.

When inflammation of the urinary system is detected, patients are often prescribed antibiotics. One of the effective drugs of this group is Monural.

Monural

Monural is a modern broad-spectrum antibiotic drug.

• It is easily absorbed, enters the bloodstream almost immediately and quickly accumulates in the bladder.
• After just a couple of hours, the drug reaches the maximum concentration necessary to destroy pathogenic microorganisms.
• Monural is effective against many known gram-negative and gram-positive bacteria, including those that are resistant to other antibiotics.

Compound

The active ingredient of Monural is fosfomycin. The preparation contains saccharin, sucrose and tangerine or orange flavorings as excipients.

Release form

• The drug is available in the form of granular powder, from which you need to prepare a suspension for oral administration.
• The powder is packaged in sachets of 2-3 g. The package contains 1-2 sachets.

The average price of Monural 2 g is about 384-448 rubles, and the drug in 3 g bags costs approximately 469-528 rubles.

Operating principle

Monural has a bactericidal effect. The mechanism of action of the drug is to suppress the synthesis of bacterial cells at the very initial stage. As a result, further proliferation of bacterial microorganisms becomes impossible.

• In addition, the drug has an anti-adhesive effect, which manifests itself in preventing the adhesion of bacterial microorganisms to cellular receptors of the uroepithelium.
• The drug is bactericidal active against almost all bacteria of gram-positive and gram-negative forms.
• Monural quickly and highly effectively affects bacteria, especially those that cause infections in the lower genitourinary tract.

Compared to antibiotic drugs such as Norfloxacin or Cotrimoxazole, Monural has a pronounced effect on microorganisms such as Proteus, Escherichia coli and Klebsiella pneumoniae. The antibiotic destroys bacterial strains that produce β-lactamase. It is effective in the treatment of pathologies caused by pathogens resistant to other antibiotics from a number of fluoroquinolones and aminoglycosides, sulfonamides and quinolones, tetracyclines, nitrofurans, etc.
Video review of the drug Monural:

Indications

The main indications for the use of Monural are:

• Acute attacks of cystitis of bacterial origin;
• Nonspecific bacterial urethritis;
• Massive asymptomatic bacteriuria, even in pregnant women;
• Urogenital infections occurring during the postoperative period;
• For prophylaxis during surgical procedures and diagnostic transurethral procedures.

Monural is especially widely used for inflammatory lesions of the bladder. This pathology is characterized by very unpleasant symptoms, which significantly worsen the quality of life and bring patients a lot of discomfort and suffering. The advantage of Monural over other drugs is its ability not to inhibit growth, but to destroy bacterial microorganisms. The drug inhibits the synthesis of the bacterial wall, causing its development to stop and death to occur.

Many studies conducted in world-famous clinics confirm the highest effectiveness of the drug in the treatment of urological diseases and its speed of action at minimal doses.

This is a kind of pill for cystitis, which you only need to take once or twice to get rid of the pathology forever. The antibiotic has a powerful destructive effect on most known bacteria, which allows it to be used in the form of empirical therapy when the specific causative agent of the pathological process has not yet been identified and its sensitivity to the drug has not been determined.

The drug is almost completely eliminated through the renal system, which eliminates its accumulation in the intestines and the development of dysbacteriosis complications. And due to the short course, the development of resistance to Monural in bacterial microorganisms is also excluded. Even after a single dose, a stable concentration of the active ingredient is achieved.

Instructions for use

The antibiotic is characterized by excellent tolerability in patients, as well as the absence of negative effects on the fetus, so it is allowed to be taken during pregnancy:

• For cystitis, adults take Monural 3 g once; if necessary, the dose can be repeated a day later. The contents of the sachet should be dissolved in 1/3 glass of water and drunk.
• For children over 5 years of age, a dosage of 2 g of the drug is indicated, also in a single dose.
• Pregnant women take the antibiotic according to a regimen similar to other adults, but it should only be prescribed by a doctor for vital indications, since the active substance of the drug is still able to penetrate the placenta. Although in the first trimester taking any medications (including Monural) is prohibited. But while breastfeeding, taking antibiotics is contraindicated.

Monural should be taken 2 hours before or after meals, because food slows down the absorption processes. Experts recommend that all categories of patients take an antibiotic at night, after emptying the bladder.

As a rule, one dose is enough per course. An additional dose may be prescribed a day after the first for recurrent infections of bacterial origin and severe pathology, for elderly patients, or in the absence of the expected therapeutic effect, which happens when the rules of administration are violated

To prevent urinary infections during urological interventions or diagnostic procedures, take Monural twice: the first time before the procedure 3 hours, and the second dose a day after it. The drug is also prescribed for the treatment of pyelonephritis, but with such a diagnosis, the dosage is selected individually by the treating specialist, and treatment is carried out in combination with other medications.

Side effects

Adverse reactions due to treatment with Monural are extremely rare, however, patients may experience:

• Allergies in the form of skin itching and rashes;
• Nausea and vomiting reactions;
• Diarrhea;
• Heartburn;
• In case of overdose, there is a high risk of diarrhea.

If side symptoms from the gastrointestinal tract appear, experts recommend increasing fluid intake, then the unpleasant symptoms will quickly disappear.

Contraindications

The antibiotic, despite such high effectiveness and relative safety, still has a number of contraindications:

• Monural should not be taken up to 5 years of age, since in such patients the development of the renal pelvis apparatus has not yet completed and the filtration functions are not fully performed.
• Women who are breastfeeding should not take antibiotics because they pass into breast milk.
• The drug should not be prescribed if there is hypersensitivity to fosfomycin and other components of the drug.
• Severe renal failure is also a contraindication for the use of antibiotics.

special instructions

The half-life of Monural is about 2-3 days, although its action begins within 3-4 hours after administration. This is manifested in a significant reduction in painful symptoms and dysuria. Monural should be prescribed with caution to diabetic patients, because the powder contains sucrose.

During antibiotic therapy with broad-spectrum drugs, antibiotic-associated colitis may develop, which will require specific treatment to eliminate.

It is not recommended to combine antibiotic treatment with metoclopramide and drugs based on it, as this leads to a significant decrease in the concentration of the drug in urine. Also during therapy the consumption of alcoholic beverages is prohibited.
In the video about the use of the drug Monural during pregnancy:

Analogs

Analogue drugs of Monural include:

• Fosfomycin (about 400 rubles);
• Phosphoral (≈450 rubles);
• Forteraz (price unknown);
• Cystoral (≈150-180 rubles);
• Espa-Fotsin (about 570-625 rubles);
• Urophosphabol (about 200 rubles).

Cheap medications like Dioxidine, Nitroxoline, Hexamethylenetetramine, Sangviritin, 5-NOK, etc. are similar in action to Monural.

Monural is a powerful remedy that destroys pathogenic microflora in the urinary organs, and also restores the integrity of the mucous membrane damaged by bacteria. Usually the remedy is prescribed by doctors for the development of cystitis, but sometimes it is used to treat other diseases of the urinary organs. If Monural is not suitable for the patient as a treatment due to the main active ingredient or the presence of contraindications, it can be replaced with an analogue similar in composition and principle of action to Monural. Such medications should be prescribed by a doctor who will examine the patient and then prescribe the correct treatment. So, which Monural analogues are the best and cheapest, and what should you pay attention to when choosing them?

The main active ingredient of the drug is fosfomycin. In the remedy it is presented in the form of trometamol, a well-known chemical compound. This active component of the drug has a powerful specific effect on the causative agent of cystitis, but in order to achieve this, you must follow the rules for taking the drug.

Thanks to fosfomycin, the synthesis of cell walls of the causative agent of the disease is suppressed, which leads to disruption of the vital activity and proliferation of bacteria. As a result, pathogenic microorganisms die, and human health is completely restored.

It is important to note that Monural is quite safe for the human body, since the medicine exhibits a specific effect against bacteria and their enzymes. This means that the drug is not endowed with cross-resistance (if it were, there would be strong resistance of the pathogen to drugs similar in action and composition).

General description of the medicine:

• the drug is capable of destroying almost all gram-positive and gram-negative types of bacteria;
• the medicine is able to interfere with the early stage of cell wall creation, thanks to which the drug can safely be considered to have a broad spectrum of action;
• the remedy, as the instructions for use say, is capable of destroying almost all pathogens of cystitis - E. coli, Morganella, Klebsiella, as well as pathogens that can be sexually transmitted.

After taking Monural, its active components are absorbed from the digestive organs into the bloodstream within an hour. After 2-2.5 hours, the maximum concentration of the drug is observed in the bloodstream, and after 4-5 hours the active substances penetrate into the urine, where they remain for 24 hours.

It is important to note that the drug must be taken once, as this is quite enough to create a powerful concentration of fosfomycin in the bladder. That is why the course of taking Monural is usually 1 day. In some cases, the concentration of the main active substance in the urine remains for 48 hours - in this case, the medicine completely cures cystitis in 99% of cases, if, of course, the drug was correctly prescribed by a doctor.

The medicine is excreted from the body along with urine. ¼ of Monural leaves the body through the intestines.

The drug is available in powder form, from which you need to prepare a solution for internal use. The powder contains granules with a pleasant fruity aroma - they dissolve easily in water, so preparing your own solution for oral administration is quite simple.

In addition to the main active ingredient, the powder also contains:

• lactose;
• sugar;
• a tangerine or lemon based flavoring that makes the medicine taste good.

Analogues of Monural may have a similar composition, as well as the principle of action on the body. Therefore, it is prohibited to search for similar remedies on your own, otherwise it will lead to serious health problems.

High-quality and frequently prescribed analogues of Monural

Although Monural has proven itself in the treatment of genitourinary diseases, and it has almost no contraindications, sometimes patients look for analogues of this drug. As a rule, this is due to the high price of the medicine, because it can be taken by all people, including children and pregnant women, since it is absolutely safe for health.

Ureacid and Urolisin are considered effective and inexpensive analogues (European and Russian).

This medicinal product, endowed with a powerful bactericidal effect, is produced in the form of granules, from which a solution for oral administration is prepared.

1 sachet contains 3 grams of the main active substance (fosfomycin, presented in the form of trometamol).

Ureacid is an antimicrobial and antibacterial agent that is allowed to be taken by all patients diagnosed with cystitis, namely adults, children over 12 years of age and the elderly.

Taking the medicine is required to get rid of infections that have developed as a result of the activation of microorganisms that are sensitive to the main substance of the medicine (fosfomycin).

How to take the medicine correctly?

1. Pour the contents of one sachet into a glass and fill it halfway with cold water.
2. After this, thoroughly mix the solution so that the granules are completely dissolved in it, and then immediately drink the medicine.

Usually the drug needs to be taken only once, like Monural. For adults and elderly people, a single dosage is 3 grams or one sachet. For children and adolescents over 12 years of age, the dose of the medicine is slightly reduced.

Side effects of the drug include:

• nausea;
• heartburn;
• diarrhea;
• dysfunction of the gastrointestinal tract.

Contraindications for Ureacid include renal failure, high levels of creatinine in urine and blood, as well as high sensitivity of the body to the components of the drug.

This analogue of Monural is available in the form of granules, which must be taken orally. The active components of Urolysin are:

• horsetail;
• birch leaf;
• glucose;
• Rowan;
• blueberry shoots and so on.

Thanks to its unique and safe composition, the medicine can be taken by all patients aged 12-75 years.

Urolisin is prescribed to patients for the treatment of mild urinary tract infections, as well as as a prophylaxis after surgical treatment of the genitourinary organs.

How to take the medicine correctly? This must be done as follows: dilute one small spoon in 100 ml of water, then mix thoroughly. You need to take the medication 3 times a day for 5 weeks. Sometimes the course of treatment lasts longer or shorter, depending on the general state of health and the severity of the disease.

Usually 2 weeks after completion of treatment, the patient is prescribed a second course.

The drug must be taken with caution by people during exacerbations of urolithiasis (and cholelithiasis), which occurs more often than once every 4 years. It is also recommended to exercise caution if the patient has large kidney stones.

Side effects of the drug include disruption of the digestive organs.

It is important to note that this medicine is sold to patients strictly according to a prescription, since if taken incorrectly it will cause serious harm to the patient’s health.

These types of Monural analogues are considered the most effective and high-quality, but drinking them without a doctor’s testimony is prohibited.

Most often, doctors prescribe them to patients, but do not forget that there are several other drugs that, in terms of action and composition, are also analogues of Monural.

Additional types of analogues

Judging by the reviews, these drugs have worked well in the treatment of cystitis. Therefore, doctors do not let them out of sight when prescribing treatment.

Additional analogues of Monural include Urophosphabol and Fosmitsin.

The release form of this antibiotic is a powder from which a solution for intravenous administration is prepared. As a rule, it looks in the form of small yellow or white granules.

The main active ingredient of the drug is fosfomycin. Urophosphabol is prescribed to patients during inflammation or infection in the pelvic organs, as well as during exacerbations of diseases of the genitourinary system. The positive aspect of the medicine is that it is prescribed to every patient in the absence of contraindications, starting from infants of the first year of life. The drug is not considered toxic, which means it will not harm the patient’s health.

How to take the medicine correctly? Since Urophosphabol is intended for intravenous administration, doctors prepare the solution for injection. The method of its preparation depends on the type and complexity of the disease. How to prepare the solution can be found in the instructions for use of the drug.

Side effects of the medication include itching, chills, convulsions, frequent dizziness, as well as skin irritation. Contraindications to the drug include high sensitivity to the main active substance, liver disease and some kidney diseases. That is why it is necessary to take the drug only as directed by a doctor.

Fosmicin

This is a well-known analogue of Monural, which is similar to it in the main active ingredient - fosfomycin, presented in the drug in the form of Trometamol. Fosmycin is available in powder form, from which it is necessary to make an intravenous solution. The drug is a broad-spectrum antibiotic that must be used systematically to completely cure diseases of the genitourinary organs. Medicine is prescribed to treat the urinary organs, as well as to maintain health after surgery on them. Children under 5 years of age are prohibited from using the drug.

Fosmicin is prescribed by the attending physician, and the dosage is prescribed to each patient individually. This depends on age, general health, and the type of disease. How doctors prepare a solution for infusion can be found in the instructions for use.

Side effects of the medicine include nausea, skin rash, vomiting and diarrhea. Contraindications to Fosmicin include the body's sensitivity to the components of the drug, as well as pregnancy and breastfeeding.

If a doctor has prescribed treatment with Monural to a patient diagnosed with cystitis, but he “cannot afford it” or the patient has contraindications, then the patient will have to replace it with a similar drug that will quickly destroy pathogenic microflora and also normalize the functioning of the genitourinary system .

It is important to note that only a doctor has the right to prescribe medicine, who will take into account all the characteristics of the body, as well as the degree and type of the disease.

Cystitis is a disease of the bladder, characterized by an inflammatory process in its walls with predominant damage to the mucous membranes. The disease is most often diagnosed in women and children. Provoking factors may be hypothermia, previous infections of the urethra, weakened immunity as a result of poor nutrition or exposure to negative factors (bad habits, poor environment, etc.).

In most cases, patients are diagnosed with infectious cystitis, which is fungal or antibacterial in nature. Treatment in this case necessarily includes taking broad-spectrum antibiotics, one of which is the fosfomycin-based drug “Monural”. “Monural” has long been used as part of complex therapy for genitourinary tract infections in adults and children, as it is one of the products with pronounced medicinal properties and proven effectiveness. Reviews from patients and doctors allow us to conclude that the drug is highly effective and safe.

To understand how the medicine works, you need to read the instructions for use.

"Monural" is a drug for internal use, which is available in the form of white soluble granules with a sharp, specific odor. The active ingredient of the granules is fosfomycin (in the form of trometamol), a substance with high antibacterial activity obtained through chemical reactions with phosphonic acid. After entering the body, fosfomycin blocks the activity of enzymes that ensure the interconversion of various substances.

"Monural" is effective not only for cystitis

"Monural" is effective in the treatment of cystitis and other inflammatory diseases of the urogenital tract caused by the following types of pathogenic microorganisms:

• Klebsiella;
• staphylococcus;
• hemophilus influenzae;
• enterococcus;
• Escherichia coli of the genus Morganella.

The mechanism of action of fosfomycin is based on disruption of the synthesis of the protein that makes up the bacterial cell wall. When the integrity of the cell membrane is damaged, microorganisms die, as they lose their ability to live and reproduce.

Note! The use of Monural when affected by certain types of pathogenic microorganisms may be ineffective due to the lack of sensitivity of bacteria to fosfomycin. Before starting antibacterial therapy, it is recommended to perform a bacterial culture to determine the causative agent of infection and its resistance to the active substance of the drug.

When is Monural prescribed?

The indication for the use of Monural is infectious cystitis of bacterial origin. Experts believe that prescribing the drug is advisable only during the period of exacerbation of the pathology, therefore it is usually not used for the treatment of chronic inflammatory lesions of the bladder.

"Monural" is prescribed if the diagnosis of "infectious cystitis of bacterial origin" is confirmed

In addition to cystitis, indications for including Monural in therapy are:

• infectious lesions of the urinary tract;
• acute urethritis;
• urethral syndrome (pain syndrome accompanying inflammatory pathologies of the urogenital tract);
• complications of infectious origin after surgical interventions on the genitourinary system.

The drug can be prescribed to prevent bladder infection after operations and diagnostic examinations that require instrumental examination of the urinary tract.

In most cases, with an uncomplicated course, a single use of the drug in the recommended dosage is sufficient. In case of relapse of the disease, repeated administration is allowed according to the regimen specified in the instructions. The medicine should be taken on an empty stomach, preferably in the evening (before bedtime). The optimal time to take the solution is 1-2 hours after dinner.

To prepare the solution, you need to pour the contents of the bag into a glass and pour in 60 ml of cold water (about a third of a glass), stir thoroughly.

Storing the prepared solution is not allowed. The Monural treatment regimen for adult patients is presented in the table below.

Scheme for using Monural for adults

Important! In some cases, individual dose adjustment may be required (for example, in patients with impaired renal function or patients over 50 years of age) or an increase in the interval between doses.

"Monural" for cystitis in children: reviews from parents

Prescription of "Monural" in pediatric practice is possible from the age of five. Cystitis in children usually occurs in an acute form with severe symptoms of intoxication, therefore the use of agents with a wide spectrum of antibacterial activity is necessary to prevent possible complications and prevent the spread of infection to the urethra.

If a child over 5 years old is diagnosed with cystitis, Monural will help

For children, Monural is available in a dosage of 2 g (per sachet). The drug contains sucrose, saccharin, as well as orange and tangerine flavors. The finished drink has a pleasant fruity taste, so there are usually no difficulties in treating children.

"Monural" - powder in sachet

Children over 5 years old need to take Monural once a day before bedtime. The duration of therapy is 1 day (unless the doctor has prescribed a different dosage regimen).

Reviews from parents

The parents of most children are satisfied with the action of the drug and its effectiveness. Many note the ease of use and short duration of treatment, as well as excellent tolerability of the drug. Side effects in the form of skin rash and moderate itching were recorded in only 7% of children receiving Monural therapy.

To whom is the drug contraindicated?

The active substance of the drug, which, after entering the systemic bloodstream, breaks down into fosfomycin and trometamol, is excreted from the body in the urine and partly with feces, therefore treatment with Monural is contraindicated for any kidney diseases accompanied by severe disturbances in the functioning of the renal system.

Treatment with Monural is contraindicated for any kidney disease

For patients whose creatinine clearance is less than 10 ml/min, the use of any agent based on fosfomycin and its derivatives is prohibited.

Important! It is also necessary to consider the possibility of intolerance or allergy to the components of the drug. In some cases, an allergic reaction may occur to the active substance itself or to auxiliary components, for example, fragrances. If the patient develops allergy symptoms during treatment, it is necessary to take an antihistamine and consult a doctor.

How quickly does the effect occur?

The maximum concentration of the active substance in the blood plasma is achieved 2-2.5 hours after taking the medicine. Fosfomycin remains active for 48 hours. Two days are usually enough for the complete disappearance of symptoms and relief of the patient’s condition.

Treatment of cystitis with Monural: patient reviews

Most of the patients who used the medicine to treat acute or recurrent cystitis are satisfied with the results obtained. After taking the drug, they note the following therapeutic effect:

• reduction in the intensity of pain or its disappearance;
• reduction of itching and pain during bladder emptying;
• normalization of body temperature (within 48 hours);
• restoration of normal consistency and color of urine.

Feedback from a patient who took Monural

Despite the high effectiveness and rapid therapeutic effect, some patients are dissatisfied with the drug due to serious side effects. In some cases, patients experienced allergic skin reactions (rash, itching) or serious digestive disorders: diarrhea, constipation, heartburn, abdominal and epigastric pain, vomiting. If the drinking regime is not sufficient, many patients report severe headaches while taking Monural.

"Monural" as a quick help for cystitis. Review

Important! The listed side effects in all cases completely disappeared after cessation of treatment. Additional symptomatic therapy is usually not required.

Video - How to drink Monural for cystitis

Treatment of cystitis in the elderly: reviews of the drug

Patients over 50-55 years old often have problems with the kidneys and organs of the urinary system, this is especially true. Cystitis is considered the most common genitourinary disease in older women. Prescribing Monural to this category of patients helps eliminate the cause of the inflammatory process and prevent the development of complications and secondary infection. The dosage of the drug for patients with various forms of renal failure should be prescribed only by the attending physician after studying the results of a laboratory urine test.

The drug is well tolerated in older people, but most often the course of therapy is extended to two days in a row. This is due to delayed absorption of fosfomycin. After Monural, continued antibacterial treatment with penicillin drugs or antibiotics from the macrolide group may be required.