Spray and lozenges Grammidin (for children, Neo with anesthetic): instructions and use. Instructions for use of Grammidin tablets and reviews Grammidin instructions for use of lozenges
Treatment of a sore throat during the cold season becomes an urgent issue not only for adults, but also for children. The pharmaceutical industry produces many dosage forms. However, are all drugs safe and can be used to treat children?
The drug "Grammidin" is a medicine with an antibacterial effect, the main active substance of which is gramicidin C, which is part of the group of polypeptide antibiotics. The drug is active against gonococci, meningococci, streptococci, and a bacteriostatic effect is observed in significant quantities.
The drug comes in different forms: tablets, paste, medicinal solution.
It would be interesting to know what kind of reviews Grammidin gets from doctors regarding its composition:
- The composition of the drug is balanced. The dosage of the antibiotic allows for effective treatment of all diseases of the throat and mouth.
- Gramicidin C today has established itself as one of the most effective substances that suppress pathogenic flora in the oral cavity. Therefore, the drug acts quickly and safely.
Indications
The tablet form is prescribed for diagnosing infectious and inflammatory lesions of the throat and oral cavity:
- gingivitis;
- stomatitis;
- acute pharyngitis;
- angina;
- periodontal disease;
- tonsillitis.
The drug in the form of a paste is usually used in the treatment of wounds and burns, since the drug “Grammidin” acts as a local antibacterial agent. Alcohol, water and fat solutions are also prescribed for burns, ulcers, purulent wounds, bedsores, and furunculosis. The product is used to irrigate tampons and bandages, and when washing wounds. The drug "Grammidin" with an anesthetic contains a special substance - oxybuprocaine, which provides an antiseptic and local anesthetic effect, which is also supported by the action of lidocaine. This medication is successfully used to treat diseases of the oral cavity.
If the patient adheres to a comprehensive treatment plan, the drug can be used in the treatment of infected eczema of the eyelids, barley, otitis externa, scleritis, blepharitis, and iritis.
Contraindications
The drug is not prescribed if intolerance to the main active ingredient, gramicidin C, is detected. In addition, external forms cannot be used in the treatment of skin affected by dermatoses. The drug is not prescribed during pregnancy and lactation. The drug "Grammidin" is used to treat children over four years of age.
Side effects
The medication can cause an allergic response, hemolysis - in the case of parenteral administration, phlebitis, contact dermatitis. The drug containing an anesthetic may cause short-term loss of sensation in the tongue.
Directions for use
- Mixing an aqueous solution: the drug “Grammidin” 2% is diluted with sterile or ordinary drinking water (100-200 times).
- Mixing a fat solution: the medicine is diluted in castor oil, lanolin or fish oil (25-30 times).
- Preparation of an alcohol solution: the dose of medication is diluted in 70% ethanol (100 times). The prepared solutions are used to treat the affected areas three times a day.
- The tablet form is taken two pills four times a day.
- The paste is applied to the affected areas in a thin layer, the wound is covered with a gauze bandage.
Special instructions
Injecting the solution into a vein is considered unacceptable due to the risk of developing phlebitis and hemolysis. Freshly prepared solution can be used within three days.
The product "Grammidin neo" - what is it?
The composition of this drug, in addition to gramicidin C, contains cetylpyridinium chloride monohydrate. The product is available exclusively in tablet form and is used to treat infections and inflammations of the throat and oral cavity.
The medication “Grammidin Neo”, reviews of which are purely positive, is recommended to be taken according to the following scheme:
- The product is used after eating, not chewed, but dissolved in the mouth.
- After use, you must refrain from eating and drinking for two hours.
- The dosage for adults and children over 12 years of age is three to four tablets per day.
- Children from four to twelve years old are prescribed one pill once or twice a day.
Use of the drug to treat children
Manufacturers have developed a mild formula of the remedy - “Grammidin for children”, which is used to treat children from four to twelve years old. Most often, the drug is prescribed for the symptomatic treatment of conditions such as pharyngitis, tonsillitis, gingivitis, stomatitis and periodontitis. In addition, the antiseptic successfully copes with other diseases that are accompanied by pain in the throat and mouth.
The composition of the children's medicine is represented by two active substances - gramicidin C (with antimicrobial action) and cetylpyridinium chloride, which acts as an antiseptic. The release form of the drug “Grammidin for children” is uniform and is presented in lozenges.
The medication is contraindicated in children under four years of age, patients who show hypersensitivity to the components of the drug, and children suffering from phenylketonuria.
It is interesting that parents themselves note the effectiveness of the drug “Grammidin”. Reviews about the effect of the drug on children's health are as follows:
- When a child is diagnosed with a purulent formation in the throat, the doctor prescribes the medication “Grammidin”. The drug is taken four times a day after meals, and after five days a very good result is revealed. It is gratifying that the lollipops are sweet, so they are easily absorbed by children. The medicine is given a solid "A".
- The child may develop an allergy from the medicine. However, after stopping treatment, the symptoms of dermatitis completely disappear. Nevertheless, the throat medication "Grammidin" for children (the reviews fully correspond to this) really heals. However, kids sometimes complain that after taking lollipops an unpleasant tingling sensation remains on the tongue.
Consumer opinion
- This is an excellent drug, the analgesic effect occurs almost instantly and helps relieve sore throat. In addition, the reproduction and growth of pathogens affecting the oral cavity is suppressed. Thanks to this medicine, even with very severe pain in the throat, swallowing is facilitated and a very pleasant feeling of freshness remains in the mouth. The drug "Grammidin neo" helps to cope well with the disease.
- The drug can be a real godsend for those people who are tired of looking for an effective remedy for their throat. Most lozenges are ineffective if severe inflammation occurs. The medicine "Grammidin" (reviews fully confirm this) helps almost immediately. After just two days of this therapy, the redness goes away and the pain recedes almost completely. A multifaceted attack on microbes is provided by the unique composition of the drug, which includes an anesthetic component, an antiseptic and an antibiotic.
- If you urgently need to relieve a sore throat, this medication is simply irreplaceable. This is especially important for those people whose profession is related to voice and speech. After a course of therapy with this drug, the throat does not hurt for a long time. However, most people report severe dry mouth due to the action of the antibiotic.
Medical opinion
- Many doctors buy this drug for their home medicine cabinet. This is an excellent antiseptic for the throat and mouth, suitable for treating all family members. The cost of the product is slightly higher than that of analogues, but it is worth it. If you use the drug strictly according to the instructions, you can quickly feel the expected effect. The tablets must be dissolved thoroughly. The antiseptic will help relieve the condition of sore throat, pharyngitis, and infectious diseases of the gums. The drug has a pleasant mild taste.
- The drug "Grammidin for children", reviews of which are heard more and more often, is one of the few medications prescribed for the treatment of children. Its balanced, safe composition helps to quickly eliminate throat diseases in children starting from the age of four. The product has a pleasant taste, and therefore children take these lollipops with pleasure.
- Many practicing dentists prescribe this drug to their patients to treat oral diseases. It effectively relieves the acute phase of inflammation and helps heal ulcers and wounds. Complex therapy becomes much more effective.
- Grammidin neo tablets are the only remedy that can be purchased at a pharmacy without fear without providing a prescription form. It is truly safe if taken exactly as recommended in the instructions.
Instead of completing
The modern pharmacological drug “Grammidin” (reviews from doctors and patients fully confirm this) is included in the home medicine cabinets of many families. It helps to heal a sore throat for both adults and children, allowing them to return to a normal lifestyle and excellent health.
Analogues
These are drugs belonging to the same pharmaceutical group, which contain different active substances (INN), differ in name, but are used to treat the same diseases.
- - Aerosol for inhalation dosed 0.125 mg/dose
Indications for use of the drug Grammidin
Infectious and inflammatory diseases of the oral cavity and pharynx, incl. accompanied by severe pain (for Grammidin® with anesthetic):
Acute pharyngitis;
Tonsillitis;
Periodontal disease;
Gingivitis;
Stomatitis.
Release form of the drug Grammidin
lozenges; polymer jar (jar) 10 cardboard pack 1;
Lozenges; contour packaging without cells 10 cardboard pack 1;
Lozenges; contour packaging without cells 10 cardboard pack 2;
Lozenges; contour packaging 10 cardboard pack 1;
Lozenges; contour packaging 10 cardboard pack 2;
Lozenges; polymer jar (jar) 20 cardboard pack 1;
Compound
Grammidin®
gramicidin C 1.5 mg
excipients: sugar; milk sugar; methylcellulose; calcium stearate
in a blister pack or a blister-free pack 10 pcs.; in a cardboard pack 1 or 2 packs or in a polymer jar 10 or 20 pcs.; in a cardboard pack 1 jar.
Grammidin® with anesthetic
Lozenges 1 table.
gramicidin C 1.5 mg
lidocaine hydrochloride 10 mg
excipients: eucalyptus oil; citric acid; menthol; aspartame; mannitol; hydroxypropylcellulose Klucel (hyprolose); calcium stearate; flavoring - lemon or raspberry, or black currant; or without flavoring
10 pcs in blister or cellless packaging; in a cardboard pack 1 or 2 packs or in a polymer jar 10 or 20 pcs.; in a cardboard pack 1 jar.
Pharmacodynamics of the drug Grammidin
Antibacterial drug for local use in the oral cavity and pharynx. Has a pronounced antimicrobial effect. In high concentrations, it has a bactericidal effect on most gram-positive and gram-negative microorganisms - causative agents of infectious diseases of the oral cavity and pharynx.
Increases the permeability of the microbial cell membrane, which disrupts its stability and causes death. The drug is practically non-addictive to microorganisms sensitive to it. When absorbed, it increases salivation, helping to cleanse the oropharynx of microorganisms and inflammatory exudate.
Pharmacokinetics of the drug Grammidin
Due to low systemic absorption, data on the pharmacokinetics of Grammidin are not available.
Use of the drug Grammidin during pregnancy
Grammidin is contraindicated for use during lactation. The drug should be used with caution during pregnancy.
Contraindications to the use of the drug Grammidin
Lactation;
Hypersensitivity to the components of the drug.
The drug Grammidin is a combination drug for the treatment of diseases of the oropharynx with infectious etiology. Available in the form of lozenges. There are several forms of medication. There are regular Grammidin, separately for children and with the addition of an anesthetic. Available without a prescription. The duration of drug therapy is no more than 14 days.
Compound
Instructions for use of Grammidin contain information about the composition of the drug. It includes:
- active ingredient gramicidin C;
- cetylpyridinium chloride;
- auxiliary connections.
The active component belongs to the group of antibiotics. Belongs to a number of tyrothricine substances. Has a wide spectrum of action. Affects staphylococcus and streptococcus, which are often the causes of inflammation. Basically, it exhibits greater activity against a group of gram-positive microorganisms.
Long-term use does not cause the development of resistance.
Cytylpyridinium chloride belongs to the group with an antiseptic effect. Affects the growth and development of pathogenic microbes. During resorption, increased salivation occurs. This helps to quickly cleanse the oral cavity of pathogenic flora.
Grammidin tablets with anesthetic additionally contain oxybuprocaine, which has a pronounced analgesic effect: the sensitivity of the nerves decreases, and the sensation of sore throat decreases. The combined action of an anesthetic and antibacterial compound ensures a rapid treatment effect.
Auxiliary components include:
- silicon dioxide in small quantities;
- talc substance;
- mint sweetener;
- sorbitol;
- magnesium stearate.
They do not affect the disease in any way.
Action
Grammidin tablets help against all infectious pathologies of the oropharynx. This happens due to its antimicrobial and antiseptic action. A drug with an active antibiotic in its composition reduces the activity and growth of microbes, this is achieved through the formation of a bactericidal and bacteriostatic effect. Accordingly, the death of a certain type of microbe occurs.
Grammidin C affects the synthesis of proteins in the cellular structure. Glycoprotein inhibition occurs. This is the main protein in the cell that is responsible for its growth. For this reason, lysis of the microbial cell develops.
Thanks to this effect, inflammation decreases and symptoms subside. Grammidin with an anesthetic also has an analgesic effect. If you have a severe sore throat, you should use this type of medicine. The drug is effective for diseases of the pharynx with a microbial nature.
In addition to the main effect, an antiseptic effect is added. Taking Grammidin provides a complex effect on pathogens of oropharyngeal diseases. Their activity decreases, their growth and development slows down.
Due to this, signs of inflammation are reduced. The pain in the throat subsides and the tickling sensation disappears. If there is no improvement with the use of the medicine, you should consult a doctor.
What is it produced in and how is it stored?
- ordinary;
- with anesthetic;
- children's
There are 6 pieces on the blister. One package contains 3 such blisters. The green color of the packaging indicates regular Grammidin. If there is a red scarf on the container, it means it contains anesthetic tablets. For children, a package with a yellow scarf. The tablets themselves are white and sweet.
Dispensed from a pharmacy without a prescription. They should be stored in a dry place out of reach of children. Do not store the packaging in direct sunlight or at temperatures above 25 degrees. Shelf life: no more than 2 years. It is indicated on the packaging. After expiration, do not use.
In what cases is Grammidin used?
The medicine Grammidin is prescribed for pathology of the oropharyngeal cavity. Indications for use are as follows:
- angina;
- laryngitis or pharyngitis;
- stomatitis, inflammation of the gums (gingivitis);
- chronic tonsillitis.
Sore throat is a disease caused by pathogenic flora in the oral cavity. Since Grammidin has a bactericidal, antiseptic and analgesic effect, it is prescribed for sore throat. The effect is formed from the first dose.
It is important that throat tablets with Grammidin must be dissolved slowly. Due to this, the action will last longer.
You can use Grammidin for a cough if the cause of the cough is an infectious process in the oropharynx. In general, this medicine does not have an antitussive effect..
Indications for the use of children's Grammidin are similar. But it is only allowed from 4 years old.
How is it distributed in the body?
According to the annotation for the medicine, its use does not affect the general condition of the body. Has only local effect. This means that it is almost not absorbed into the systemic circulation. With prolonged use, a small proportion of the active substance may enter the bloodstream. In this case, it is excreted through the renal system from the body.
Contraindications
There are a number of contraindications to the use of Grammidin. These include:
- individual intolerance to the main components of the drug;
- development of allergies;
- first trimester of pregnancy;
- children under 4 years of age.
Intolerance to the main components can occur in the form of an allergic reaction on the skin or oral mucosa. You should pay attention to the formation of redness on the mucous membrane in the oral cavity. Itching and red spots may occur on the skin. Allergies develop both to the first use and to subsequent uses.
Grammidin is not recommended for use during lactation. When used topically, a small portion may enter the bloodstream. Then the active substance is filtered through the vessels into milk. You should not use the drug yourself without a doctor's recommendation.
Interaction with other drugs
Simultaneous use with other antibacterial drugs enhances their effect. This group includes substances for both local and systemic use.
Methods of administration
According to RLS, Grammdin should be prescribed only for local therapy. The drug should not be taken orally. The tablets should be dissolved slowly after meals, not chewed. After use, do not drink or eat food for 1 hour. This will allow the active substance to have a therapeutic effect.
For children over 12 years of age and all adults, take 1 tablet, no more than 6 tablets per day. It is better to keep the medicine under the tongue during resorption. This will allow the medication to dissolve faster.
For children aged 4 to 12 years, the maximum daily dose is no more than 3 tablets. The duration of therapy is a week. If the drug does not help within 7 days, you should tell your doctor.
Undesirable effects and overdose
Side effects occur with long-term use. The development of allergies to the first and subsequent doses is noted. In this case, you should stop using the substance.
Long-term use may cause gastrointestinal problems. Especially in people with chronic gastrointestinal diseases. Nausea and heartburn occur. In rare cases, vomiting is observed.
In addition to the effect on the gastrointestinal tract, a feeling of numbness in the oral cavity may form. But this happens in rare cases. This complication is caused by Grammidin with an anesthetic.
Due to low absorption, systemic side effects are rare.
Long-term use may cause the following effects:
- from the gastrointestinal tract, severe nausea followed by vomiting;
- diarrhea occurs.
If such symptoms appear, you should stop taking it.
According to the instructions, it should not be used if there are open surfaces in the oral cavity. This is due to the fact that the drug slows down the regeneration processes in the wound. Does not affect the ability to use the vehicle. There are no special instructions for people working with high concentration levels. Available only in tablet form. There is no spray form with Grammidin.
Contraindicated for phenylketonuria, as it contains aspartame.
Used both for monotherapy and in combination with other medicinal substances.
The price of Grammidin depends on its type. In general, the cost ranges from 300 rubles. One package may not always be enough for a course of throat treatment.
In case of severe pain, Grammidin should be used with an anesthetic.